Preparation method of vitamin E

Abstract

The invention discloses a preparation method of vitamin E. Vitamin E is prepared from trimethylhydroquinone and isophytol by condensation, wherein the condensation is performed in the presence of a Bronsted-Lewis ionic liquid catalyst, and structures of the Bronsted-Lewis ionic liquid catalyst are shown as formulae (A), (B) and (C) in the description. The preparation method has the advantages thatequipment is little corroded, little wastewater is produced, the catalyst is recyclable and easy to separate and losses little, the reaction selectivity is good, the yield is high and the like.

Description

technical field [0001] The invention belongs to the technical field of organic synthesis, and in particular relates to a preparation method of vitamin E. Background technique [0002] Vitamin E is the general term for tocopherol compounds. It is a golden or light yellow viscous oily liquid with a mild and special smell. Vitamin E is miscible with acetone, ether or vegetable oil, almost insoluble in water, and is a fat-soluble antioxidant. Vitamin E can be divided into two categories: natural vitamin E and synthetic vitamin E. At present, synthetic vitamin E accounts for more than 80% of the global total commodity volume. [0003] In industrial production, vitamin E is generally synthesized by condensation of 2,3,5-trimethylhydroquinone and isophytic alcohol. Traditional processes usually use Lewis acid or protonic acid as the catalyst for the condensation reaction. However, the traditional process will cause equipment corrosion and increase equipment costs. Second, waste...

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Problems solved by technology

However, the process requires supercritical carbon dioxide as a solvent to achieve high concentration and yield, and there is still room for improvement in the repeatability of ionic liquids.

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