Natural antioxidant compound

A compound antioxidant and natural technology, applied in the direction of anti-toxic agents, drug combinations, plant raw materials, etc., can solve problems such as no related reports, achieve the effects of wide sources, enhanced antioxidant activity, and reduced raw material costs

Active Publication Date: 2018-05-04
CHANGSHA UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no relevant report on the process of compound enzymatic hydrolysis and extraction of the mixed medicinal materials of Salvia miltiorrhiza-Kudzu root-hawthorn leaf-corn silk

Method used

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  • Natural antioxidant compound
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0018] 1 Experimental materials

[0019] Salvia miltiorrhiza, kudzu root, hawthorn leaf, and corn silk (parts by weight: 4-7.5 parts by weight of salvia miltiorrhiza, 1-2.5 pieces of kudzu root, 1-3 hawthorn leaf, and 1-3 corn silk) were placed in a blast drying oven, dried at 40°C for 24 hours, and pulverized. , passed through a 60-mesh sieve, and placed in a desiccator for later use.

[0020] Enzymes: cellulase, pectinase

[0021] 2 extraction process

[0022] Take 1 g of medicinal materials, add 144 mg of cellulase and 14.4 mg of pectinase, add 40 mL of water, keep the temperature at 65°C for 2 hours, and collect the filtrate by filtration. Add 40mL of 70% ethanol to the filter residue, extract at 65°C for 2h, filter, combine all filtrates, and dilute to a 100mL volumetric flask with water. The resulting extract was lyophilized into powder after rotary evaporation. According to the formula (1) to calculate the powder yield. Take an appropriate amount for DPPH clearance...

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PUM

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Abstract

The invention discloses a natural antioxidant compound, which is prepared from the following components in parts by weight: 4 to 7.5 parts of radix salviae miltiorrhizae, 1 to 2.5 parts of radix puerariae, 1 to 3 parts of folium crataegi, and 1 to 3 parts of corn stigma. Four medicines are compounded and extracted through an enzymolysis-alcohol water combined extraction process, and various activeingredients such as flavonoids, phenolic acid and polysaccharide can be extracted to form the antioxidant compound, so that on one hand, a synergistic interaction effect can be achieved, on the otherhand, the different types of active ingredients can mutually repair and regenerate to form an oxidation reduction cycle system, and the antioxidation activity of the natural antioxidant compound is remarkably improved compared with a single medicine extract. In addition, the folium crataegi and the corn stigma are wide in source and cheaper than the radix salvia miltiorrhizae and the radix puerariae, so that the raw material cost is reduced.

Description

technical field [0001] The invention relates to a natural compound antioxidant. Background technique [0002] Antioxidants are additives that can prevent or delay product oxidation and prolong storage life, including natural antioxidants and chemically synthesized antioxidants. Due to the toxic and side effects of chemical antioxidants, people are constantly looking for natural antioxidant ingredients from plants. Facts have proved that plants contain many natural antioxidant ingredients, and the toxicity of natural antioxidants is far lower than that of synthetic antioxidants. And studies have shown that the combined use of multiple antioxidants is often greater than the effect of using a single antioxidant at the same dose, that is, antioxidants often have synergistic antioxidant effects, and the plant extract itself is a mixture. The performance extract is compounded into a compound natural antioxidant according to an appropriate ratio, and its effect will be greatly imp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P39/06
CPCA61K36/899A61K36/488A61K36/537A61K36/734A61K2236/333A61K2236/19A61K2300/00
Inventor 赵晨曦刘琳琪
Owner CHANGSHA UNIVERSITY
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