Enteral nutrition preparation containing konjac mannan oligosaccharide and L-glutamine and application

A technology of enteral nutrition preparation and mannose oligosaccharides, which is applied in the field of medicine, can solve problems such as lowering blood lipids, achieve blood sugar regulation, facilitate popularization and application, and have good patient compliance

Active Publication Date: 2018-04-20
WUHAN GENERAL HOSPITAL OF GUANGZHOU MILITARY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The Mechanism of Konjac Mannooligosaccharides in Lowering Blood Lipids Has Not Been Fully Elucidated

Method used

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  • Enteral nutrition preparation containing konjac mannan oligosaccharide and L-glutamine and application
  • Enteral nutrition preparation containing konjac mannan oligosaccharide and L-glutamine and application
  • Enteral nutrition preparation containing konjac mannan oligosaccharide and L-glutamine and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A preparation method of an enteral nutrition preparation combining konjac manna oligosaccharides and L-glutamine:

[0022] Dissolve 16g of konjac mannan oligosaccharides in 100mL of physiological saline, and then add 3g of L-glutamine to obtain it.

Embodiment 2

[0024] The therapeutic effect of an enteral nutrition preparation combined with konjac manna oligosaccharides and L-glutamine on model hyperlipidemia rats:

[0025] 1. Effect of an enteral nutrition preparation combining konjac manna oligosaccharides and L-glutamine on the body weight of model hyperlipidemic rats

[0026] Rat group introduction: the control group is the negative control group; the model group is the hyperlipidemia group without intervention; KMOS-L is the low-dose KMOS experimental group; KMOS-M is the medium-dose KMOS experimental group; KMOS-H is the high-dose KMOS experimental group. Dose KMOS experimental group; KMOS-HL is combined high-dose KMOS and L-glutamine group. Except for the control group, the rest of the groups were model groups fed high-fat diet. As shown in Table 1, from the beginning of the experiment to the end of the fourth week, there was no significant difference in the body weight of the rats in each group. At the end of the fifth week, ...

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Abstract

The invention belongs to the technical field of medicines, and particularly discloses an enteral nutrition preparation containing konjac mannan oligosaccharide and L-glutamine and application thereofin hyperlipoidemia nutritional therapy. When the method is adopted in the nutritional therapy of a hyperlipoidemia rat model, a certain curative effect is realized, no toxic and side effects exist, the preparation method is simple, the preparation raw materials are easy to obtain, and the application prospect is wide.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to an enteral nutrition preparation combined with konjac mannan oligosaccharides and L-glutamine, and also relates to the application of the enteral nutrition preparation in nutrition treatment of hyperlipidemia. Background technique [0002] Epidemiological studies have shown that the incidence of atherosclerosis and coronary heart disease is closely related to hyperlipidemia, while the levels of triglyceride (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) increase A decrease in high-density lipoprotein cholesterol (HDL-C) levels is an important indicator of hyperlipidemia. Increased TC levels are one of the important causes of atherosclerosis, and HDL-C can transport TC in peripheral tissues to the liver for decomposition into bile acid, activate lecithin cholesterol transfatty acylase, and catalyze the esterification of TC. Can reduce serum TC leve...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/702A61K31/198A61P3/02A61P3/06
CPCA61K31/198A61K31/702A61K2300/00
Inventor 韩芳李晓迪刘晔
Owner WUHAN GENERAL HOSPITAL OF GUANGZHOU MILITARY
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