Application of Yangxinshi Tablets in Preparation of Drugs for Treating Depression
A technology for Yangxin's tablet and depression, applied in the field of medicine, can solve problems such as no reports on the application of Yangxin's tablet as an antidepressant drug, and achieve the effects of good development prospect, less side effects and definite curative effect.
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example 1
[0010] Example 1: Effect test of Yangxinshi Tablets on rats with chronic mild unpredictable stimulus depression
[0011] 1 Experimental method
[0012] 1.1 Experimental animals and grouping
[0013] Experimental animals were provided by Shanghai Xipuer-Bikay Experimental Animal Co., Ltd.: 80 SD male rats, SPF grade, weighing 180-220 g, animal production license number: SCYK (Shanghai) 2013-0016. Before the experiment, the rats were placed in a normal experimental environment for adaptive feeding, food and water were provided normally, and a 12-hour light cycle was ensured. The 80 rats were randomly divided into blank control group, model group, fluoxetine group, high-dose Yangxinshi Tablets group, medium-dose Yangxinshi Tablets group, and low-dose Yangxinshi Tablets group.
[0014] 1.2 Animal modeling and administration
[0015] During the model preparation process, rats in the model group, fluoxetine group, high-dose Yangxinshi Tablet group, medium-dose Yangxinshi Tablet...
example 2
[0050] Example 2: Effect test of Yangxinshi tablets on mice with vascular depression induced by cerebral ischemia-reperfusion
[0051] 1 Experimental method
[0052] 1.1 Experimental animals and grouping
[0053] Experimental animals were provided by Shanghai Xipuer-Bikay Experimental Animal Co., Ltd.: 90 ICR male mice, SPF grade, weighing 18-22g, animal production license number: SCYK (Shanghai) 2013-0016. Before the experiment, the mice were placed in a normal experimental environment for adaptive feeding, food and water were provided normally, and a 12-hour light cycle was ensured. The 90 mice were randomly divided into sham operation group, model group, fluoxetine group, High-dose Yangxinshi Tablets group, medium-dose Yangxinshi Tablets group, and low-dose Yangxinshi Tablets group.
[0054] 1.2 Animal modeling and administration
[0055] After the mice in the model group, fluoxetine group, high-dose Yangxinshi tablet group, middle-dose Yangxinshi tablet group, and low...
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