Preparation method of antibacterial peptide gynecologic washing lotion
A peptide gynecological and lotion technology, which is applied in the field of preparation of antibacterial peptide gynecological lotion, can solve the problems of accelerated vaginal aging, long preparation time, lack of synergistic effect, etc., to increase solubility and absorption rate, improve active ingredients and yield , increase the effect of sterilization and anti-inflammation
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Embodiment 1
[0031] A preparation method of antimicrobial peptide gynecological lotion, comprising the following steps:
[0032] 1) Take honeybees, place them in an environment containing Gardnerella and Bacteroides for 1 to 2 hours, then heat at 50°C for 2 hours, dry the whole insects, add licorice tablets, and grind to obtain bee powder; the licorice tablets and honeybees The mass ratio is 1:8; the honeybee is Apis mellifera; the particle diameter of the honeybee powder is 1mm;
[0033] 2) Put the honeybee powder into the glycerin-acetic acid solution containing glucose, soak for 30 hours, and then ultrasonically vibrate for 10 minutes to obtain a mixed solution; the volume fraction of glycerol in the glycerin-acetic acid solution is 15%; The concentration of the solution is 0.5mol / L;
[0034] 3) Filter the mixed solution to remove the filter residue, freeze the filtrate at -10°C first, and then dehydrate and dry it under 2Pa vacuum condition to obtain honeybee extract;
[0035] 4) Pre...
Embodiment 2
[0037] A preparation method of antimicrobial peptide gynecological lotion, comprising the following steps:
[0038] 1) Take honeybees, place them in an environment containing Gardnerella and Bacteroides for 1 to 2 hours, then heat at 70°C for 1 hour, dry the whole insects, add licorice tablets, and pulverize them to obtain bee powder; the licorice tablets and honeybees The mass ratio is 1:10; the honeybee is a high-yielding honeybee of royal jelly; the particle diameter of the honeybee powder is 5mm;
[0039] 2) Put the honeybee powder into glycerol-acetic acid solution containing glucose, soak for 40 hours, and then ultrasonically vibrate for 20 minutes to obtain a mixed solution; the volume fraction of glycerol in the glycerin-acetic acid solution is 30%; The concentration of the solution is 1mol / L;
[0040] 3) Filter the mixed solution to remove the filter residue, freeze the filtrate at -30°C first, and then dehydrate and dry it under 10Pa vacuum condition to obtain the h...
Embodiment 3
[0043] A preparation method of antimicrobial peptide gynecological lotion, comprising the following steps:
[0044] 1) Take honeybees, place them in an environment containing Gardnerella and Bacteroides for 1 to 2 hours, then heat at 60°C for 1.5 hours, dry the whole insects, add licorice tablets, and pulverize them to obtain bee powder; the licorice tablets and honeybee The mass ratio of the honeybee is 1:9; the honeybee is Anatolia honeybee; the particle diameter of the honeybee powder is 1-5mm;
[0045] 2) Put the bee powder into the glycerol-acetic acid solution containing glucose, soak for 35 hours, and then ultrasonically vibrate for 15 minutes to obtain a mixed solution; the volume fraction of glycerol in the glycerin-acetic acid solution is 20%; The concentration of the solution is 0.8mol / L;
[0046]3) Filter the mixed solution to remove the filter residue, freeze the filtrate at -20°C first, and then dehydrate and dry it under 5Pa vacuum condition to obtain honeybee ...
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