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Film coating agent for treating chronic eczema

A technology for chronic eczema and film coating agent, applied in the field of film coating agent preparation, can solve problems such as intractability to cure, bacterial infection, etc., and achieve the effects of not polluting clothes, easy to accept, and excellent curative effect

Inactive Publication Date: 2018-02-06
CHENGDU SHENGSHI GUANGHUA BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Many clinical treatments are still difficult to cure
At present, symptomatic treatment is mostly used clinically, and there are bacterial infections that cannot be ignored in the treatment, especially the lesion site has affinity for Staphylococcus aureus

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0026] The film coating agent for the treatment of chronic eczema of the present embodiment is represented by weight, and is made up of calamine powder 20g, paeonol 10g, ethylene glycol 100g, polyvinyl alcohol 4g, ciclopirox olamine 1g, and ethanol 800g.

[0027] The preparation method of above-mentioned compound treatment chronic eczema varnish comprises the following steps:

[0028] (1) Add 20g of calamine powder and 10g of paeonol into 250g of ethanol, stir and dissolve with a magnetic stirrer, and obtain a mixed solution for use;

[0029] (2) Sprinkle 4g ​​of polyvinyl alcohol evenly to make it swell naturally;

[0030] (3) Add 1.0g of ciclopirox olamine, put it in a 1200ml large beaker, keep stirring, and add ethanol to 1000mL;

[0031] (4) Use a pH regulator to adjust the pH to 6.0~7.0, stir well, and then it can be used as a medicine for treating chronic eczema.

[0032] When the solution is acidic, use a mass fraction of 85% sodium carbonate solution as a pH regulato...

Embodiment 2

[0035] In the above-mentioned embodiment, the present embodiment is further expressed by weight, and is composed of 20 g of calamine powder, 10 g of paeonol, 100 g of ethylene glycol, 4 g of polyvinyl alcohol, 1 g of ciclopirox olamine, and 800 g of ethanol. Other steps in this embodiment are the same as those in the above embodiment, and will not be repeated here.

Embodiment 3

[0037] In this embodiment, in the above embodiment, further, the viscosity of the polyvinyl alcohol is 50 mPa·s, and the degree of deacetylation is not less than 80%. Other steps in this embodiment are the same as those in the above embodiment, and will not be repeated here.

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PUM

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Abstract

The invention discloses a film-coating agent for treating chronic eczema, expressed by weight, consisting of 15-42g of calamine powder, 7-23g of paeonol, 83-125g of ethylene glycol, 2-8g of polyvinyl alcohol, Composition of ciclopirox olamine 0.5~2.1g, ethanol 500~900g. In the present invention, calamine powder and paeonol have obvious effects on inhibiting bacteria, and calamine powder and paeonol are prepared into medicine, and due to the ciclopirox amine transdermal technology, the penetrating power of medicine skin limbs has been increased, It shows the superior curative effect of the coating agent on chronic eczema; the chronic eczema medicine made of polyvinyl alcohol has no greasy feeling, is easy to spread, has strong adhesion, has a certain tear resistance strength, is easy to use, and is non-toxic to the skin. irritating.

Description

technical field [0001] The invention relates to the field of coating agent preparation, in particular to a coating agent for treating chronic eczema. Background technique [0002] Eczema is a skin inflammatory reaction caused by complex internal and external factors. Chronic eczema is generally limited and has infiltration and hypertrophy, severe itching, and easy recurrence. The etiology of the disease is complex, and internal and external factors interact, often in many ways. Patients often have allergic constitution, which is related to genetic factors, so it occurs in specific groups of people. [0003] Acute eczema is an inflammatory skin disease of the epidermis and superficial dermis caused by a variety of internal and external factors. It has a variety of rashes and exudation tendencies, accompanied by severe itching, and is prone to repeated attacks. It is often related to allergic reactions. In the early or acute stage, the clinical symptoms are patches of eryth...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/30A61K9/70A61K47/10A61K47/32A61K47/22A61P17/00A61K31/12
CPCA61K33/30A61K9/7015A61K31/12A61K47/10A61K47/22A61K47/32A61K2300/00
Inventor 张蛟
Owner CHENGDU SHENGSHI GUANGHUA BIOTECH CO LTD
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