Medicine composition for treating depression and method for preparing medicine composition

Abstract

The invention relates to a medicine composition for treating depression and a method for preparing the medicine composition, and belongs to the field of traditional Chinese medicines. The medicine composition comprises components including, by weight, 8-12 parts of radix ginseng, 8-12 parts of radix bupleuri, 10-14 parts of radix scutellariae, 8-12 parts of rhizoma pinelliae preparatum, 8-12 partsof ramulus cinnamomi, 8-12 parts of rhizoma zingiberis, 7-9 parts of semen ziziphi spinosae, 8-12 parts of radix curcumae, 13-17 parts of ossa draconis, 13-17 parts of concha ostreae, 3-5 parts of fructus jujubae and 8-12 parts of radix glycyrrhizae preparata. Outstanding curative effects can be realized by the various components in the weight ranges. The medicine composition and the method havethe advantages that the medicine composition comprises traditional Chinese medicines such as the radix ginseng, the radix bupleuri and the radix scutellariae, the radix ginseng is sweet in taste and slightly warm in nature and mainly acts in spleens and lung channels, the radix bupleuri is bitter in taste and slightly cold in nature and has certain pharmaceutical activity for regulating immune systems, effects of tranquilizing mind and relieving pain can be realized by the radix bupleuri, effects of clearing heat, drying dampness, stopping bleeding and preventing miscarriage can be realized bythe radix scutellariae, effects of drying dampness and resolving phlegm can be realized by the rhizoma pinelliae preparatum, obvious effects for treating the depression can be realized by the ramuluscinnamomi, the rhizoma zingiberis, the semen ziziphi spinosae and the like, and the medicine composition is applied to an accumulative number of years for the time being, is used for more than 300 cases and accordingly has solid clinical foundations and theoretical foundations.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating depression and a preparation method thereof. Background technique [0002] Depression is also known as mood disorder syndrome in modern times. The onset is manifested as depressed mood, slow thinking and no interest in anything. Patients with more serious conditions may have suicidal thoughts or even suicide behaviors, and some patients with depression may experience hallucinations. There is no specific age limit for depression, and problems such as anxiety, poor body feeling, and poor sleep may occur, which will cause serious harm to the patient himself and his loved ones. Depression belongs to the category of emotional diseases in traditional Chinese medicine. In recent years, the incidence of depression has been increasing, showing an increasing trend. Some relevant organizations predict that until 2020, depression will T...

AI Technical Summary

Problems solved by technology

①As a CRH receptor antagonist, antalarmin can reverse the changes brought about by chronic stress to a certain extent; ②R278995 / CRA0450 ​​is the latest CRF receptor antagonist synthesized in the medical field. However, there is also a dose-dependent effect; ③ Mifepristone, as a GR modulator, has a rapid and obvious curative effect, and it can show a very obvious antidepressant effect within 5 days after administration, and it can not only antagonize with excessive cortisol , so that the overall structure and function of the frontal cortex and brainstem are avoided as much as possible, and there are still some potential effects, but the current medical field has not thoroughly studied its potential functions, and further research is needed; ④Desipramine and Amitriptyline can directly act on GR, thereby continuously increasing its ability to interact with glucocorticoids, and continuously enhancing the activity of the receptor until it recovers, resulting in a stronger and more sensitive feedback effect of the HPA axis on GC. Reversal of abnormal behavior in depressed patients

However, there are still certain limitations in the treatment of depression based on acupuncture and moxibustion. In future research, it is necessary to organically combine acupuncture and moxibustion with drug therapy and psychotherapy in order to provide more effective treatments for depression. method

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