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Nicotine ditatrate and preparing method thereof

A technology of nicotine salt and nicotine, which is applied in the treatment of tobacco, tobacco, application, etc., can solve the problems of strong volatility, unstable content and color, etc., and achieve the effects of stable content, soft aroma and reduced irritation

Inactive Publication Date: 2018-01-05
CHANGNING DEKANG BIOTECH SHENZHEN CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to alleviate the stimulation of nicotine, make the e-cigarette liquid taste better and be easier to inhale, in tobacco, most of nicotine exists in a stable state combined with organic acids, such as citric acid and malic acid, to form a salt, using industrial Purified nicotine is an unpleasant, bitter, clear oily liquid, highly volatile, easily oxidized into a light yellow liquid in the air and under light, and its content and color are extremely unstable

Method used

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  • Nicotine ditatrate and preparing method thereof

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preparation example Construction

[0033] A preparation method of nicotine salt, comprising the following steps:

[0034] Mix and stir the organic acid and nicotine to react to obtain nicotine salt;

[0035] In terms of parts by mass, the organic acid is 30-60 parts, and the nicotine is 40-60 parts.

[0036] In this application, the organic acid is acidic, and the nicotine is strongly basic, and they are mixed at a certain ratio and then reacted to obtain a stable nicotine salt.

[0037] Preferably, the process of mixing and stirring the organic acid and nicotine specifically includes the following steps:

[0038] Mix organic acid with organic solvent, heat and stir it, mix and stir with nicotine after cooling, and react to obtain liquid nicotine salt;

[0039] Wherein, the ratio of the organic solvent to the organic acid is (0.8-1):1, more preferably the ratio of the organic solvent to the organic acid is 1:1.

[0040] An organic solvent is added to facilitate the reaction and obtain liquid nicotine salt. ...

Embodiment 1

[0060] A kind of preparation method of liquid nicotine salt, concrete steps are as follows:

[0061] (1) Prepare 1 kg of nicotine salt;

[0062] (2) 30% of oxalic acid is weighed to be 300g, 30% of propylene glycol is weighed to be 300g, and the ratio of oxalic acid to propylene glycol is 1:1;

[0063] (3) adding oxalic acid and propylene glycol to a glass beaker;

[0064] (4) Place the glass beaker on the heater, start to heat up and reach a constant temperature of 70 degrees; start stirring from the heating process for 20 minutes and stop heating after fully dissolving to obtain an oxalic acid solution;

[0065] (5) After the oxalic acid solution drops to normal temperature, take 40% pure nicotine to be 400g, and add it to the oxalic acid solution;

[0066] (6) After the oxalic acid solution is mixed with pure nicotine, the mixed solution becomes turbid and spontaneously generates heat, and the reaction procedure starts. After 3 hours, the mixed solution stopped reacting ...

Embodiment 2

[0068] A preparation method of liquid nicotine salt, specifically comprising the following steps:

[0069] (1) Prepare 1 kg of nicotine salt;

[0070] (2) taking by weighing 30% of malic acid is 300g, taking by weighing 30% of propylene glycol is 300g, and the ratio of malic acid and propylene glycol is 1:1;

[0071] (3) Add malic acid and propylene glycol to a glass beaker;

[0072] (4) Place the glass beaker on the heater, start to heat up and reach a constant temperature after reaching 70 degrees; start stirring from the heating process for 20 minutes and stop heating after fully dissolving to obtain the malic acid solution;

[0073] (5) After the malic acid solution drops to normal temperature, take 40% pure nicotine to be 400g, and add it in the malic acid solution;

[0074] (6) After the malic acid solution is mixed with pure nicotine, the mixed solution becomes turbid and spontaneously generates heat, and the reaction procedure starts. After 3 hours, the mixed soluti...

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Abstract

The invention provides nicotine ditatrate and a preparing method thereof. The method comprises the following step of mixing and stirring organic acid and nicotine to be subjected to a reaction to obtain nicotine ditatrate, wherein nicotine ditatrate is prepared from, by mass, 30-60 parts of organic acid and 40-60 parts of nicotine. Pure nicotine and organic acid are mixed, and the preparing methodhas the advantages of being easy to operate, convenient to manufacture and safe. Prepared nicotine ditatrate is stable in state, the content of nicotine is stable and is not attenuated, the color oftobacco tar is unchanged, the irritation of nicotine is lowered, nicotine is more easily inhaled, the fragrance of electronic tobacco juice is tender, throat hit is comfortable, nicotine ditatrate ismore easily accepted by a user and the production and selling are promoted, nicotine ditatrate is suitable for being widely popularized in the field of electronic cigarettes, and prepared solid nicotine ditatrate does not easily leak in packaging, and is safer and convenient to transport, store and use.

Description

technical field [0001] The invention relates to the technical field of preparation and application of electronic cigarette liquid, in particular to a nicotine salt and a preparation method thereof. Background technique [0002] E-cigarettes are electronic products that mimic cigarettes and have the same look, smoke, taste and feel as cigarettes. It is a product that allows users to inhale after turning nicotine, etc. into steam by means of atomization. [0003] Nicotine, commonly known as nicotine, is an alkaloid present in Solanaceae plants (Solanum genus), an important component of tobacco, and a representative of N choline receptor agonists. Both have effects on the central nervous system and have no clinical application value. Nicotine can be addictive or dependent, and repeated use of nicotine also increases heart rate and blood pressure and reduces appetite. Large doses of nicotine can cause vomiting and nausea, and in severe cases, people can die. [0004] In orde...

Claims

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Application Information

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IPC IPC(8): A24B15/12A24B15/28
Inventor 郑俊祥郑志炫
Owner CHANGNING DEKANG BIOTECH SHENZHEN CO LTD
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