Plant source itch mite killing spray and preparation method thereof

The technology of plant source and scabies mites is applied in the field of plant source scabies mites killing spray and its preparation field, which can solve the problems of drug residues, environmental hazards and the like, and achieve the effects of being convenient to carry, good in curative effect, and simple and easy to prepare.

Inactive Publication Date: 2017-12-22
SICHUAN AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is easy to cause global disasters such as drug residues, environmental hazards, and drug resistance

Method used

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  • Plant source itch mite killing spray and preparation method thereof
  • Plant source itch mite killing spray and preparation method thereof

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preparation example Construction

[0028] The invention also discloses a preparation method of a plant-derived scabies-killing spray, comprising the following steps:

[0029] (1), soak Eupatorium adenophorum powder by adding methanol, soak at room temperature for 24 hours, soak 3 times, wherein, the volume fraction of methanol is 60%-100%, the mass fraction ratio of Eupatorium adenophorum powder to methanol (g / ml ) is 1:4-8;

[0030] (2), the filtrate soaked in step (1) is collected, evaporated to dryness with a rotary evaporator to the extract, then extracted with a mixture of methanol, ethyl acetate and water, and evaporated to dryness in the upper organic phase obtained by extraction. Extract, for later use; wherein, the volume ratio of methanol: water: ethyl acetate = 1:4:5;

[0031] (3), weigh the extract after step (2) extraction, add ethanol to dissolve, and add activated carbon, the mass fraction of activated carbon is 1%-6%; stir 0.5-1.5 hours under the condition of 35-45 ℃ water bath, filter, The fi...

Embodiment 1

[0036] A botanical acaricidal spray comprises, in parts by mass, 0.1 part of Eupatorium adenophorum extract, 2.4 parts of an emulsifier, 20 parts of a cosolvent, 2.5 parts of a transdermal agent, and 75 parts of a solvent.

[0037] In this implementation case, the emulsifier is Tween-80, the cosolvent is absolute ethanol, the transdermal agent is laurozone, and the solvent is distilled water.

[0038] The preparation method of botanical acaricide comprises the following steps:

[0039] (1) Take a certain amount of Eupatorium adenophorum powder, add 6 times of 80% methanol to soak at room temperature and shake it on a shaker for 24 hours, soak for 3 times, and collect and combine several filtrates. Evaporate to dryness with a rotary evaporator, and extract with methanol: water: ethyl acetate = 1:4:5, and evaporate the upper organic phase obtained by extraction to extract to extract for later use.

[0040] (2) Weigh 3 parts of the medicinal extract described in step (1), add 3 ...

Embodiment 2

[0043] A botanical acaricidal spray comprises, in parts by mass, 0.3 part of Eupatorium adenophorum extract, 1 part of emulsifier, 43 parts of cosolvent, 0.7 part of transdermal agent and 55 parts of solvent.

[0044] In this implementation case, the emulsifier is Tween-80, the cosolvent is absolute ethanol, the transdermal agent is laurozone, and the solvent is distilled water.

[0045] The preparation method of botanical acaricide comprises the following steps:

[0046] (1) Take a certain amount of Eupatorium adenophorum powder, add 4 times of 100% methanol to soak at room temperature and shake on a shaker for 24 hours, soak for 3 times, and collect and combine several times of filtrate. Evaporate to dryness with a rotary evaporator, and extract with methanol:water:ethyl acetate (ml:ml:ml) = 1:4:5 extract, evaporate the upper organic phase obtained by extraction to extract, and set aside.

[0047] (2) Weigh 1 mass part of the medicinal extract described in step (1), add 6 m...

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Abstract

The invention discloses plant source itch mite killing spray and a preparation method thereof. The spray is prepared from the following ingredients in parts by mass: 0.1 to 1 part of eupatorium adenophorum extracts, 1 to 10 parts of emulsifiers, 20 to 50 parts of latent solvents, 0.5 to 2.5 parts of transdermal agents and 40 to 75 parts of solvents. The invention also discloses a preparation method of the plant source itch mite killing spray. The method comprises the following steps of preparing the eupatorium adenophorum extracts; weighing all ingredients according to the proportion; uniformly stirring the weighed eupatorium adenophorum extracts, the emulsifiers, the latent solvents, the transdermal agents and the solvents; performing bottling to prepare the spray. The plant source itch mite killing spray has the efficacies of resisting bacteria, diminishing inflammation, diminishing swelling and relieving itching; a better curative effect is achieved on itch mites; the effective rate reaches up to 100 percent; the preparation method is simple; the implementation is easy; the carrying is convenient.

Description

technical field [0001] The invention belongs to the field of medicine preparation, and in particular relates to a plant source scabies-killing spray and a preparation method thereof. Background technique [0002] Scabies is caused by scabies mites that live in the epidermis of the skin of humans, domestic animals, and wild animals. [0003] Scabies can cause symptoms such as severe itching at the infected part of the sick animal, crusting of the epidermis, local hair loss at the infected part, and thickening of the skin. Domestic animals and pets such as goats, pigs, dogs, cats, and rabbits, as well as wild animals such as giant pandas, camels, elk, reindeer, gazelles, llamas, bushes, and antelopes have been infected. [0004] At present, in the treatment of mites, most of the antibiotics represented by ivermectin are the main ones. It is easy to cause global disasters such as drug residues, environmental hazards, and drug resistance. Contents of the invention [0005] ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/53A61K9/12A61P33/14
CPCA61K9/0017A61K9/12A61K36/53A61K47/22A61K2236/33A61K2236/333A61K2236/39A61K2236/55
Inventor 胡延春翁嘉华许锐光石真胡力文符杰
Owner SICHUAN AGRI UNIV
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