Probe machine achievement method and device based on DNA computing

Abstract

The embodiment of the invention provides a probe machine achievement method and device based on DNA computing. The method comprises the steps that preset conditions are obtained according to a mathematical problem to be solved, and DNA sequence coding is conducted on DNA origami structures and DNA single-strands according to the preset conditions respectively; a database containing the DNA origami structures is built; a probe library containing the DNA single-strands is built; the DNA origami structures and the DNA single-strands are subjected to hybrid reaction on a computing platform to obtain a reaction product; the reaction product is detected through a detector to obtain a computing result. According to the method, the DNA origami structures and the DNA single-strands in DNA computing are used, so that a probe machine is built to improve the processing ability of a computer, and the computing result is easy to detect; the problem is effectively solved that the mispairing rate of self-assembling of traditional algorithms is high, and the reliability of the computing result is improved, and free communication between data in a three-dimensional space and specificity assembling are achieved.

Description

technical field [0001] Embodiments of the present invention relate to the technical field of biological computers, in particular to a method and device for realizing a probe machine based on DNA computing. Background technique [0002] In the course of its development, electronic computers have always followed Moore's Law and made great contributions to the development of human civilization. However, the development of electronic computers has encountered huge obstacles so far. There are two main points: First, the manufacturing technology of electronic computers is about to reach its limit. Second, due to the Turing machine model, electronic computers have not been able to deal with large-scale NP-complete problems. [0003] Due to the unique principle of complementary base pairing of DNA molecules and its superior structural characteristics, it is especially suitable as an element of the construction system. DNA molecule is a typical nano-scale substance, its structural...

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Problems solved by technology

[0005] The embodiment of the present invention provides a method and device for realizing a probe machine based on DNA calculation, which is used to solve the disadvantages of the traditional computer in the prior art that the calculation efficiency is not high enough, the result detection process is cumbersome, the reliability is low, and it is not intuitive.

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