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Micro-column gel card agglutination test result identification system and blood type analyzer

A technology of micro-column gel cards and detection results, which is applied in the field of medical devices, can solve the problems of affecting analysis results, too large interception area, and incomplete reaction area, etc., and achieve the effect of improving versatility and accuracy

Active Publication Date: 2018-10-16
SUZHOU HYBIOME BIOMEDICAL ENG CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned method of directly intercepting the image of the reaction area of ​​a fixed size in the microtube for analysis is only applicable to a certain size of the microcolumn gel card. When the width of the microcolumn gel card used is different, the intercepted reaction area It is not comprehensive, or the interception area is too large, which may affect the final analysis results and cause misjudgment.

Method used

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  • Micro-column gel card agglutination test result identification system and blood type analyzer
  • Micro-column gel card agglutination test result identification system and blood type analyzer
  • Micro-column gel card agglutination test result identification system and blood type analyzer

Examples

Experimental program
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Effect test

Embodiment 1

[0055] Such as figure 1 As shown, it is a microcolumn gel card agglutination detection result recognition system of the present invention, including: an image acquisition module for collecting microcolumn gel card images that have undergone agglutination and centrifugation; a microtube image interception module for intercepting The microtube image in the microcolumn gel card image; the target area acquisition module, used to acquire the target area that needs to be identified in the microtube image, and the target area is the image area within the inner wall of the microtube; effectively The reactant area capture identification module is used to capture the effective reactant area in the target area, and identify the position and relative area of ​​the captured effective reactant area; the standard setting module is used for the user to pre-set the judgment standard; and The judging output module is used for judging and outputting the agglutination detection result of the micr...

Embodiment 2

[0059] On the basis of Example 1, the effective reactant area capture identification module is used to identify the target area. The effective reactant area capture identification module includes: a bright area search and identification unit, which is used to find and identify the position of the bright area in the microtube; The position and relative area of ​​the tube. The above-mentioned bright area is the image area where the gray value in the target area is greater than or equal to the first threshold, that is, the area where the red blood cells in the microtubules are concentrated, such as image 3 , 7 and area A in 8. According to experience, the first threshold gray value generally takes a value in the range of 108-128. The sub-bright area is the image area where the gray value in the target area is greater than or equal to the second threshold and less than the first threshold, that is, the area where the red blood cells in the microtubules are scattered, such as ...

Embodiment 3

[0078] Such as image 3 In the shown embodiment 3, a result confirmation module is added on the basis of the embodiment 1 or 2, and it is necessary to manually confirm the results output by the judgment output module. For example, after the judgment output module judges the result, it outputs the judgment result in the form of a pop-up window or other forms, and requires manual confirmation of the result, and the system ends the identification work after confirmation. After manual confirmation, the system misjudgment caused by instrument failure or other reasons is avoided.

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Abstract

A micro-column gel card agglutination test result identification system comprises: an image collection module, a micro-tube image capturing module, a target region acquisition module, an effective reactant region capturing and identification module, a standard setting module, and a determining and outputting module. The system performs fitting with respect to a boundary of an inner wall of a micro-tube automatically by means of a binary processing unit and a fitting and line-drawing unit and acquires a reaction region within the boundary of the inner wall of the micro-tube to be a target region for analysis, thus preventing a portion of the image outside the region from interfering with the analysis and determination, effectively increasing the accuracy of determination, thereby enabling the system to be applied to a variety of micro-column gel cards having different specifications and improving the universality thereof for analyzers of different specifications. The accuracy of result identification is increased by performing a classification determination, based on both a brightness position and relative area, on the effective reactant region in the target region under analysis, and then performing a comparative analysis of a coarse classification and a fine classification.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and relates to a microcolumn gel card agglutination detection result recognition system and a blood type analyzer. Background technique [0002] At present, clinical blood testing generally adopts the cassette detection method with simple operation, clear results and stability. To control the size of the gel gap, so that the gap can only allow free red blood cells to pass through, so that free red blood cells and aggregated red blood cells are separated. The detection principle is: when the antigen and antibody react, the blood cells agglutinate, and when centrifuged, the agglutination cannot pass through the gap of the gel, but stays in the upper layer of the gel tube, and the reaction is positive. Unagglutinated blood cells can pass through the gel gap during centrifugation and settle at the bottom of the gel tube, giving a negative reaction. [0003] In an automated blood analyzer, t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/80G01N21/84
CPCG01N21/8483G01N33/80
Inventor 吴锋闫晓磊沙利烽
Owner SUZHOU HYBIOME BIOMEDICAL ENG CO LTD
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