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Probiotic gel particles and preparation method thereof

A technology of probiotics and gel, which is applied in the direction of bacteria, bifidobacteria, and yeast-containing food ingredients used in food preparation, can solve the problems that limit the effective use and promotion of probiotic products, and do not improve the intestinal colonization rate, taste and Problems such as poor user experience can help prevent and treat intestinal flora-related diseases, improve reasonable distribution, and withstand storage and transportation.

Inactive Publication Date: 2017-10-20
李立风
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AI Technical Summary

Problems solved by technology

However, traditional probiotic products have defects such as low bacterial activity, low viable bacteria rate, poor intestinal colonization effect, and can only be stored and transported at low temperature.
Although new probiotic-related products such as freeze-dried bacteria powder and bacteria tablets can be stored at room temperature, they have no anti-digestive effect, nor have the function of improving intestinal colonization rate; probiotic capsules have a certain anti-digestive effect, but the taste and usage Poor experience, which limits the effective use and promotion of probiotic products

Method used

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  • Probiotic gel particles and preparation method thereof
  • Probiotic gel particles and preparation method thereof
  • Probiotic gel particles and preparation method thereof

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preparation example Construction

[0023] The preparation method of probiotic core body can be carried out according to the following method:

[0024] The above-mentioned probiotic core body can be obtained by adsorbing and mixing the probiotic cells on the carrier, and then making them into solid particles.

[0025] In detail, the probiotics can be activated and multiplied first to obtain the probiotic liquid, and the probiotic liquid is mixed with the carrier solution to make solid particles to obtain a bacterial cell content of 5×10 8 -2×10 9 CFU / g of probiotic core body is enough. The carrier solution can be at least one of carbohydrate solution, protein solution and lipid solution, and the mass concentration of the carrier solution can be 1-5%. The specific method for making solid particles above can be to condense the mixture of the bacterial solution and the carrier solution at low temperature, for example: mix the mixture of agar and oligosaccharides with the bacterial solution, and condense at -2 to ...

Embodiment 1

[0039] Lactic acid bacteria liquid (1 × 10 11 CFU / mL, 1mL) mixed with 2wt% sodium alginate solution (100mL), added dropwise to 3wt% calcium chloride solution and solidified for 20min, to obtain the core body of probiotics (thalline content in the core body of probiotics made is 1×10 9 CFU / g).

[0040] Put the probiotic core body in 2wt% sodium alginate and 10wt% oligosaccharide solution and mix for 5 minutes, take it out, and then place it in 3wt% calcium chloride solution to solidify for 20 minutes to obtain a single-layer gel particle; The colloidal particles were mixed in 2wt% sodium alginate and 10wt% oligosaccharide solution for 5 minutes, taken out, and solidified in 3wt% calcium chloride solution for 20 minutes to obtain double-layer gel particles; 2wt% sodium alginate and 10wt% oligosaccharide solution were mixed for 5 minutes, taken out, and finally placed in 3wt% calcium chloride solution to solidify for 20 minutes to obtain probiotic gel particles with a water act...

Embodiment 2

[0042] Lactic acid bacteria liquid (1 × 10 11 CFU / mL, 1mL) mixed with the mixed solution (100mL) of the oligosaccharide of 2wt% and 1wt% agar, under the condition of -2 ℃, low-temperature condensation 20min, obtains the core body of probiotics (in the core body of probiotics made) The cell content is 1×10 9 CFU / g).

[0043] Place the probiotic core body in 2wt% sodium alginate and 2wt% oligosaccharide solution for 5 minutes, take it out, and solidify it in 4wt% calcium chloride solution for 20 minutes to obtain a single-layer gel particle; place the single-layer gel particle Put it in the mixed solution of 3wt% sodium alginate and 10wt% oligosaccharide for 5 minutes, take it out, and then place it in 4wt% calcium chloride solution to solidify for 20 minutes to obtain double-layer gel particles; then place the double-layer gel particles in 3wt% Sodium alginate and 10wt% oligosaccharide mixed solution for 5 minutes, taken out, and finally placed in 4wt% calcium chloride soluti...

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Abstract

The invention relates to the food field, and particularly relates to probiotic gel particles and a preparation method thereof. The method comprises thallus adsorption and gel wrapping, wherein the thallus adsorption comprises mixing vectors with probiotic thalli so as to obtain probiotic core bodies, and the gel wrapping comprises wrapping the probiotic core bodies with outer gel layers. The water activity of the obtained probiotic gel particles is 0.10-0.99. The method generates little damage to the probiotics, and can reserve enough activated probiotic thalli. The probiotic gel particles prepared by the preparation method have good storage and transportation performance. The probiotics have high colonization efficiency in intestinal tracts when eaten.

Description

technical field [0001] The invention relates to the field of food, and in particular to probiotic gel particles and a preparation method thereof. Background technique [0002] Scientific research in recent years has shown that the structure of intestinal microflora is not only related to common digestive tract diseases, but also related to depression, diabetes, hypertension, obesity, intestinal cancer, inflammation and other diseases, and is also related to the development of children's immune system and antibiotic resistance , tumor treatment effect and other health factors are closely related. Probiotics can prevent and assist diseases related to them by establishing a reasonable structure of human intestinal flora, and have a beneficial effect on health. However, traditional probiotic products have defects such as low bacterial activity, low rate of viable bacteria, poor intestinal colonization effect, and can only be stored and transported at low temperature. Although ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/135A23P10/30
CPCA23L33/135A23P10/30A23V2002/00A23V2400/51A23V2200/32A23V2250/76
Inventor 李立风
Owner 李立风
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