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Phospholipid preparations for improving communication skills

一种制剂、磷脂酸的技术，应用在磷脂制剂领域，能够解决没有报道、改善ASD患者口头或非口头沟通、体重增加等问题

Active Publication Date: 2021-10-15
ENZYMOTEC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these medical interventions benefit challenging behaviors, but they have not been reported to improve verbal or non-verbal communication in ASD patients
Additionally, they have significant side effects, including weight gain, sedation, and extrapyramidal effects

Method used

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  • Phospholipid preparations for improving communication skills
  • Phospholipid preparations for improving communication skills
  • Phospholipid preparations for improving communication skills

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0120] Embodiment: the effect of preparation of the present invention in autistic patients

[0121] Preparation of Phospholipid Composition: Lipid preparation was prepared as follows: marine lecithin produced by the extraction method of biomass from krill was dissolved in an organic solvent and mixed with L-serine, CaCl2, phospholipase D (PLD) Reacts with aqueous solutions of acetate buffer. After the trans-phosphatidyl transfer reaction, the resulting mixture containing PS, PC, PA and LPA was purified by removal of the aqueous phase, evaporation of the organic solvent and further purification stages. The resulting powder mainly contains EPA, palmitic acid, DHA, oleic acid and linoleic acid bound to different phospholipids.

[0122] Table 1 - List of ingredients in one capsule (167 mg per capsule) containing phospholipid formulation

[0123] parameter Specification Phosphatidylserine n.l.t.75mg / capsule Phosphatidylcholine n.l.t.0.0165mg / capsule ...

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PUM

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Abstract

The formulations of the present invention were found to be effective for the majority of patients diagnosed with autism. In patients characterized by language delay and non-expressive / non-emotional communication patterns, the formulations of the present invention were found to be more effective in patients diagnosed with autism without language delay and with expressive / emotional communication modes, Even though all patients took the formulation for a similar amount of time. Specific analysis of the type and quality of improvements detected within the patient group characterized by delayed language development and non-expressive / non-affective communication patterns revealed that most patients improved in multiple communication skills: speech, language, conversation and sociality game.

Description

[0001] field of invention [0002] The present invention relates to phospholipid formulations effective in improving the communication ability of subjects suffering from communication impairment / difficulty. [0003] Background of the invention [0004] Communication is the sending, receiving or exchanging of ideas, information, signals or messages that enable individuals or groups to persuade, seek information, give information or express emotion. This broad definition includes body language, speaking and writing skills. [0005] Communication impairment / difficulty is a developmental or acquired impairment. The American Speech-Language-Hearing Association (ASHA) more specifically describes communication disorders as affecting a person's ability to "receive, send, process, and comprehend concepts or verbal, non-verbal, and pictorial symbol systems." Communication impairments can partially or completely impede communication. [0006] Communication impairments can include, but ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/201A61K31/202A61K31/661A61K31/685A61P25/00A23L33/115A23L33/12
CPCA23L33/12A23L33/115A61K31/201A61K31/202A61K31/661A61K31/685A23V2002/00A61K2300/00A23V2200/30A23V2200/322A61P25/00A61P25/18
Inventor 达夫纳·扎勒尔·雷格夫罗伯特·丘德诺瓦雅艾尔·里克特加利·奥尔加·索里亚·阿茨
Owner ENZYMOTEC
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