High-throughput analysis method for identifying hazardous waste substances in solid wastes

Abstract

The invention discloses a high-throughput analysis method for identifying hazardous waste substances in solid wastes. The method comprises the following steps: freeze-drying, grinding and sieving: freeze-drying a solid waste sample by a freeze-dryer, grinding the freeze-dried solid waste sample by a mortar and sieving by a sieve; accelerated solvent extraction: extracting organic matters in the solid waste sample by an accelerated solvent extractor; concentration and constant volume realization: concentrating extracting solution and performing constant volume on the extracting solution, filtering the extracting solution by a filtering membrane and storing the filtered extracting solution; online detection: identifying the hazardous waste substances in a stored product with an HPLC (high performance liquid chromatography)-TOF-MS (time-off-flight mass spectrometer). A first-level mass spectrum and a second-level mass spectrum can be fast and continuously scanned simultaneously in single once analytical determination by the HPLC-TOF-MS; the hazardous waste substances are identified by comparing acquired information with a database of the hazardous waste substances and comparing the second-level mass spectrum with a standard second-level mass spectrum, so that the resolution ratio is high, and the result accuracy is high.

Description

technical field [0001] The invention belongs to the technical field of analytical chemistry, and in particular relates to a method for quickly identifying hazardous waste substances in solid waste, and more specifically relates to a high-throughput method for rapidly identifying hazardous waste substances in solid waste. Analytical method. Background technique [0002] With the rapid development of industrial production and economy, more and more chemicals have been put into production and use. Up to now, more than 120 million substances have been registered on www.cas.org, but they are controlled by relevant departments The substances in the environment only account for the tip of the iceberg of compounds in the environment. These substances will inevitably enter the environment during production, use, and disposal. The problem of environmental pollution is becoming more and more serious, mainly manifested in air, water quality, and soil pollution. The frequency of polluti...

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Problems solved by technology

[0006] Purpose of the invention: Aiming at the identification of hazardous waste in solid waste by existing methods: there will be deviations in the final screening results, some potential compounds will be ignored, and it is difficult to guarantee the effectiveness of detection; traditional tandem mass spectrometry data collection is based on prior The established multi-reaction monitoring method only measures information in a specific retention time range, and the additional information analysis of a single sample requires additional instrumental analysis, which is time-consuming and labor-intensive, and increases costs; the invention provides a method for quickly identifying hazardous waste in solid waste A high-throughput analysis method for hazardous waste-like substances, using high-performance liquid chromatography-time-of-flight mass spectrometry can quickly and rapidly analyze the primary and secondary mass spectra of hazardous waste-like substances in solid waste in a single analysis and determination Continuous scanning, screening, and identification, through the extraction and analysis of primary and secondary mass spectrograms of different substances and comparison with the self-built database, can screen out a variety of hazardous waste substances, and achieve national standards for hazardous waste The function of rapid identification of hazardous waste substances that is difficult to meet the identification standard, the screening and analysis results are more accurate

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