Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Composition for relieving uncomfortable gout symptoms and finger-print establishing method

A composition and discomfort technology, which is applied in the direction of drug combination, active ingredients of hydroxyl compounds, medical preparations containing active ingredients, etc., can solve problems such as potential safety hazards, achieve color coordination, soft taste, and improve discomfort symptoms

Active Publication Date: 2017-10-10
天津药食同源健康产业有限公司
View PDF5 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] According to research results, the above-mentioned medicines or health care products have the effect of improving the symptoms of gout, but the above-mentioned products contain traditional Chinese medicine ingredients, and there are potential safety hazards in long-term use

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Composition for relieving uncomfortable gout symptoms and finger-print establishing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] A composition for improving the symptoms of gout, formula: 20kg of grape seed extract, 6kg of grape skin extract, 10kg of red wine extract, 2kg of ginseng extract, 15kg of wolfberry extract, 5kg of cherry extract, and 15kg of green tea extract.

[0059] Above-mentioned composition is made into granule, and preparation method is as follows:

[0060] 1) Weigh the fine powder under the 80 mesh sieve of the above-mentioned raw materials according to the proportioning ratio, and mix evenly;

[0061] 2) Add the mixed fine powder into the binder, the binder is alcohol with a mass concentration of 75%, and the consumption of the binder is 5% of the sum of the mass of the remaining components. Make 40-mesh granules, dry them at 60°C for 60 minutes, and pack them separately.

experiment example 1

[0066] The efficacy of the composition was verified by selecting a specific population.

[0067] Experimental sample: the granules prepared in Example 1 and Comparative Example 1.

[0068] Volunteer population: 100 gout patients were randomly divided into two groups, who took the granules prepared in Example 1 and Comparative Example 1 respectively.

[0069] Test method: two groups of subjects took two compositions, twice a day, 1.5g each time, for one month, and observed the improvement of the common symptoms of gout in the subjects. The results are shown in Tables 1 and 2 below.

[0070] Table 1 Example 1 Gout Symptom Improvement Questionnaire (n=50)

[0071] symptom

[0072] Table 2 Comparative Example 1 Gout Symptom Improvement Questionnaire (n=50)

[0073] symptom

[0074] Based on the above experimental results, it can be seen that the two compositions have improved the reduction of uric acid and the relief of joint pain, but the effect of Example ...

experiment example 2

[0076] The granules prepared in Example 1 are detected by UHPLC, and the fingerprints are constructed, the conditions are as follows:

[0077] Instrument: Waters ACQUITY UPLC H-Class;

[0078] Chromatographic column: BEH C18, 2.1×100mm, 1.7μm;

[0079] Flow rate: 0.4mL / min; Column temperature: 20-60°C;

[0080] Mobile phase A: 0.1% formic acid aqueous solution;

[0081] Mobile Phase B: Acetonitrile

[0082] Gradient elution:

[0083] time / minute

[0084] For the constructed fingerprints, see figure 1 .

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a composition for relieving uncomfortable gout symptoms and a finger-print establishing method. The composition contains the following components in parts by weight: 50-300 parts of grape seed extract, 50-100 parts of grape skin extract, 50-200 parts of red wine extract, 10-50 parts of ginseng extract, 50-200 parts of wolfberry extract, 10-100 parts of cherry extract and 50-200 parts of green tea extract. According to the invention, various components are reasonable in formula and are used together, and the composition can effectively achieve the effect of relieving the uncomfortable symptoms caused by gout. The invention also establishes a fingerprint distinguishing mark for the product, establishes the specificity and characteristics of the product and is beneficial to the standard production of the product.

Description

technical field [0001] The invention belongs to the technical field of functional food and health food, and in particular relates to a composition capable of improving discomfort symptoms of gout and a fingerprint establishment method. Background technique [0002] High uric acid is the fourth highest after the traditional three highs of hypertension, hyperlipidemia, and hyperglycemia, and it is catching up with the previous "three highs", which seriously threatens human health. Currently, patients with hyperuricemia in China The incidence rate is 10%, that is, there are about 130 million potential people, and about 1 / 10-1 / 5 of the people with high uric acid will develop gout. Gout has become the second largest metabolic disease in China. The Chinese Medical Association issued a red Early warning, the incidence of gout is increasing at a rate of 7.5% every year. The number of gout patients in my country has reached 13.5 million, and 1 / 5 of gout patients have lost their ability...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/87A61K9/16A61P19/06A23L33/105G01N30/02A61K31/045
CPCA23L33/105A23V2002/00A61K9/1617A61K31/045A61K36/258A61K36/736A61K36/815A61K36/82A61K36/87G01N30/02A61K2300/00A23V2250/214A23V2200/30
Inventor 李赫宇张东星王磊
Owner 天津药食同源健康产业有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com