Infantile eczema cream and preparation method thereof
A technology for infant eczema and eczema ointment, which is applied in the direction of ointment delivery, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of unsatisfactory curative effect, strong side effects, slow curative effect, etc. Stimulating, mild medicinal effect
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Embodiment 1
[0034] Embodiment 1: the preparation of a kind of efficient and safe baby eczema ointment:
[0035] An ointment for baby eczema, made from the following raw materials in mass percentage: 3% shea butter, 3% coconut oil, 2% lanolin, 1.2% Scutellaria baicalensis extract, 1% Phellodendron phellodendron extract, 0.15% Cnidium chinensis extract , Kochia chinensis extract 0.3%, allantoin 0.2%, bisabolol 0.2%, menthyl lactate 0.2%, Tween-60 3.8%, Span-80 0.9%, dipotassium glycyrrhizinate 0.2%, hard 2% fatty acid, 5% stearyl alcohol, 7% glycerin, 0.1% essence, 0.2% xanthan gum, and the balance of deionized water. Formulation analysis is shown in Table 1.
[0036] Concrete preparation steps are as follows:
[0037] (1) Mix shea butter, coconut oil, lanolin, stearic acid, stearyl alcohol, Tween-60, and Span-80 evenly and heat to 75-80°C to obtain the oil phase for later use;
[0038] (2) Dipotassium glycyrrhizinate, allantoin, and menthyl lactate were added to deionized water and stir...
Embodiment 2
[0044] An ointment for baby eczema, made from the following raw materials in mass percentage: 2.92% of shea butter, 0% of coconut oil, 1.98% of lanolin, 1.18% of Scutellaria baicalensis extract, 0.94% of Phellodendron Phellodendron extract, and 0.15% of Cnidium chinensis extract , Kochia chinensis extract 0.28%, allantoin 0.18%, bisabolol 0.18%, menthyl lactate 0.1%, Tween-60 3.90%, Span-800.98%, dipotassium glycyrrhizinate 0.20%, stearin 1% acid, 5.1% stearyl alcohol, 7% glycerin, 0.08% essence, 0.21% xanthan gum, 0.14% methylparaben, 0.10% propylparaben, and the balance of deionized water. The preparation steps are the same as in Example 1.
Embodiment 3
[0045] Embodiment 3: the performance test of the baby eczema ointment prepared by embodiment 1 and 2
[0046] (1) Appearance:
[0047] Standard: The paste is delicate and uniform
[0048] Result: up to standard
[0049] (2) Physical and chemical indicators
[0050] ① cold resistance
[0051] Method: Adjust the refrigerator to -5~-10°C in advance (temperature control accuracy ±2°C), and put a bottle of the fully packaged sample in the refrigerator. Take it out after 24 hours, and observe it visually after returning to room temperature.
[0052] Result: No abnormalities such as oil-water separation.
[0053] ②Heat resistance
[0054] Method: Adjust the constant temperature incubator to (40±1)°C in advance, and place a bottle of the fully packaged sample in the constant temperature incubator. Take it out after 24 hours, and observe it visually after returning to room temperature.
[0055] Result: No abnormalities such as oil-water separation and discoloration.
[0056] (...
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