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Infantile eczema cream and preparation method thereof

A technology for infant eczema and eczema ointment, which is applied in the direction of ointment delivery, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of unsatisfactory curative effect, strong side effects, slow curative effect, etc. Stimulating, mild medicinal effect

Active Publication Date: 2017-10-10
广州希海生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the curative effect of drugs for treating eczema on the market is not satisfactory, especially since the incident of Grandma Tian was exposed on March 15, 2011, the market urgently needs a safe and reliable infant care product
On the one hand, Western medicine is currently commonly used oral antihistamines, external hormones and antiallergic ointment treatments. Although the effect is quick and can temporarily relieve symptoms, the side effects are strong, and it is easy to relapse after stopping the drug, and the baby's skin immunity is poor. Eczema-like creams are not easily accepted by the families of patients; on the other hand, baby eczema creams that use traditional Chinese medicine as anti-eczema drugs are relatively safe, but the curative effect is slow.

Method used

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  • Infantile eczema cream and preparation method thereof
  • Infantile eczema cream and preparation method thereof
  • Infantile eczema cream and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: the preparation of a kind of efficient and safe baby eczema ointment:

[0035] An ointment for baby eczema, made from the following raw materials in mass percentage: 3% shea butter, 3% coconut oil, 2% lanolin, 1.2% Scutellaria baicalensis extract, 1% Phellodendron phellodendron extract, 0.15% Cnidium chinensis extract , Kochia chinensis extract 0.3%, allantoin 0.2%, bisabolol 0.2%, menthyl lactate 0.2%, Tween-60 3.8%, Span-80 0.9%, dipotassium glycyrrhizinate 0.2%, hard 2% fatty acid, 5% stearyl alcohol, 7% glycerin, 0.1% essence, 0.2% xanthan gum, and the balance of deionized water. Formulation analysis is shown in Table 1.

[0036] Concrete preparation steps are as follows:

[0037] (1) Mix shea butter, coconut oil, lanolin, stearic acid, stearyl alcohol, Tween-60, and Span-80 evenly and heat to 75-80°C to obtain the oil phase for later use;

[0038] (2) Dipotassium glycyrrhizinate, allantoin, and menthyl lactate were added to deionized water and stir...

Embodiment 2

[0044] An ointment for baby eczema, made from the following raw materials in mass percentage: 2.92% of shea butter, 0% of coconut oil, 1.98% of lanolin, 1.18% of Scutellaria baicalensis extract, 0.94% of Phellodendron Phellodendron extract, and 0.15% of Cnidium chinensis extract , Kochia chinensis extract 0.28%, allantoin 0.18%, bisabolol 0.18%, menthyl lactate 0.1%, Tween-60 3.90%, Span-800.98%, dipotassium glycyrrhizinate 0.20%, stearin 1% acid, 5.1% stearyl alcohol, 7% glycerin, 0.08% essence, 0.21% xanthan gum, 0.14% methylparaben, 0.10% propylparaben, and the balance of deionized water. The preparation steps are the same as in Example 1.

Embodiment 3

[0045] Embodiment 3: the performance test of the baby eczema ointment prepared by embodiment 1 and 2

[0046] (1) Appearance:

[0047] Standard: The paste is delicate and uniform

[0048] Result: up to standard

[0049] (2) Physical and chemical indicators

[0050] ① cold resistance

[0051] Method: Adjust the refrigerator to -5~-10°C in advance (temperature control accuracy ±2°C), and put a bottle of the fully packaged sample in the refrigerator. Take it out after 24 hours, and observe it visually after returning to room temperature.

[0052] Result: No abnormalities such as oil-water separation.

[0053] ②Heat resistance

[0054] Method: Adjust the constant temperature incubator to (40±1)°C in advance, and place a bottle of the fully packaged sample in the constant temperature incubator. Take it out after 24 hours, and observe it visually after returning to room temperature.

[0055] Result: No abnormalities such as oil-water separation and discoloration.

[0056] (...

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PUM

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Abstract

The invention discloses an infantile eczema cream and a preparation method thereof. The infantile eczema cream is prepared from raw materials of, by weight percentage, 1-3% of shea butter, 0-4.6% of coconut oil, 1.9-5% of lanolin, 0.5-2% of scutellaria baicalensis extract, 0.4-2% of golden cypress extract, 0.05-0.2% of fructus cnidii extract, 0.1-0.5% of fructus kochiae extract, 0.1-0.5% of allantoin, 0.05-0.2% of bisabolol, 0.1-2% of menthyl lactate, 2-5% of surfactant, 0.1-0.5% of dipotassium glycyrrhizinate, 1-10% of stearic acid, 1-5.5% of octadecanol, 0.3-7% of glycerin, 0-10% of methylparaben, 0-0.5% of propylparaben, 0-1% of essence, 0.1-25% of thickener and water as balance. The infantile eczema cream is prepared from a number of Chinese herbs and gives play to the synergistic effects of the Chinese herbs, achieves the effects of heat clearing, detoxification, dampness elimination, bacteria resistance, inflammation diminishing, wind dispelling and itching relief. The infantile eczema cream is mild and rapid in effect and free from skin irritation and side effects.

Description

technical field [0001] The invention belongs to the field of biology and health, and in particular relates to a baby eczema ointment and a preparation method thereof. Background technique [0002] In recent years, the incidence of eczema in infants and young children has gradually increased, and it is often lingering and recurrent. Baby eczema ointment is the main drug for treating infant eczema, and its market demand is increasing year by year. In particular, the full liberalization of the two-child policy in October 2015 may have a more significant positive impact on the birth rate. The arrival of high-quality baby eczema cream has a huge and growing market demand. However, the curative effect of the medicines currently on the market for treating eczema is not satisfactory, especially since the incident of Granny Tian was exposed on March 15, 2011, the market urgently needs a safe and reliable infant care product. On the one hand, Western medicine is currently commonly u...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/06A61P17/00A61P31/02A61K31/045A61K31/37
CPCA61K9/0014A61K9/06A61K31/045A61K31/37A61K36/185A61K36/234A61K36/539A61K36/756A61K47/44A61K2300/00
Inventor 胡云睿迟德彪刘叔文戴开金沈志勇解娇伍林健陈坤
Owner 广州希海生物科技有限公司
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