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Traditional Chinese medicinal composition for external use for treating rash, preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine, can solve problems such as ineffective effects, affecting the quality of life of patients, and treatment that cannot be carried out normally.

Inactive Publication Date: 2017-09-26
常州桐树生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Acne / acne-like rash not only affects the quality of life of patients, but also may lead to the failure of normal treatment, seriously affecting the therapeutic effect of tumors
Acne / acneoid rash limits the application of EGFRIs to some extent
Western medicine often uses antibiotics, external hormones and other methods of treatment, the effect is not very obvious

Method used

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  • Traditional Chinese medicinal composition for external use for treating rash, preparation method and application thereof
  • Traditional Chinese medicinal composition for external use for treating rash, preparation method and application thereof
  • Traditional Chinese medicinal composition for external use for treating rash, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] Prescription: Scutellaria baicalensis 20g, purslane 30g, white moss bark 30g, flavescens 20g, dandelion 30g;

[0078] The content of baicalin in the Scutellaria baicalensis is 2.5%, the total flavonoid content of purslane in purslane is 2%, the total flavonoid content in white moss bark is 2%, the content of matrine in Sophora flavescens is 2%, The content of total flavonoids in dandelion is 1.8%. The content determination methods of the above components were determined according to the content determination methods under the items of Scutellaria baicalensis, purslane, white fresh skin, flavescens, and dandelion in the 2015 edition of the Chinese Pharmacopoeia.

[0079] Preparation method: Take the raw material according to the proportion, decoct it twice, combine the extracts, filter, concentrate under reduced pressure to a density of 1.10 (60°C), centrifuge at a high speed, and take the supernatant; according to the supernatant: glycerol: density = 2.2 : Add excipien...

Embodiment 2

[0083] Prescription: Scutellaria baicalensis 25g, purslane 40g, white moss bark 35g, flavescens 30g, dandelion 35g;

[0084] Preparation method: take the raw material drug in proportion, extract twice with 50% ethanol under reflux, combine the extracts, filter, recover ethanol, add water to dissolve, concentrate under reduced pressure to a density of 1.10 (60°C), centrifuge at a high speed, and take the supernatant; according to the above Serum: glycerol: dense = 2.2:1:2 ratio and add excipients to make external preparation.

[0085] Usage: Apply directly to the rash area or make a mask and stick it on the face.

Embodiment 3

[0087] Prescription: Scutellaria baicalensis 30g, purslane 35g, white moss bark 40g, flavescens 25g, dandelion 40g;

[0088] The preparation method is the same as in Example 1.

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Abstract

The invention provides a traditional Chinese medicinal composition for external use for treating rash. The traditional Chinese medicinal composition is prepared from the following raw medicines: 10 to 50 weight parts of radix scutellariae, 10 to 60 weight parts of herba portulacae, 10 to 60 weight parts of cortex dictamni, 10 to 50 weight parts of radix sophorae flavescentis, and 10 to 60 weight parts of herba taraxaci. The traditional Chinese medicinal composition disclosed by the invention has a remarkable effect on the aspect of improving acne-like rash and itch degree related to EGFRIs (Epidermal Growth Factor Receptor Inhibitors); moreover, an obvious adverse effect is avoided.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and its preparation method and application, in particular to an external Chinese medicinal composition for treating skin rashes, its preparation method and application, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] In recent years, the clinical application of tumor targeted therapy has been increasing year by year, and its therapeutic effect is also increasing. It will soon become a promising tumor treatment method in the 21st century. Epidermal growth factor receptor inhibitors (EGFRIs) are the most widely used clinically at present. These drugs are favored by doctors and patients for their outstanding clinical efficacy. However, its adverse reactions have various manifestations, among which rash (mainly acne / acneoid rash) is the most common. Acne / acne-like rash not only affects the quality of life of patients, but also may lead to ...

Claims

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Application Information

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IPC IPC(8): A61K36/75A61P17/00A61P35/00A61P17/04
CPCA61K9/0014A61K36/185A61K36/288A61K36/489A61K36/539A61K36/75A61K47/10A61K2236/33A61K2236/331A61K2236/333A61K2300/00
Inventor 崔慧娟王巍
Owner 常州桐树生物科技有限公司
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