Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method and application of herba ardisiae japonicae alcohol extract

A technology of tea alcohol and tea alcohol, which is applied in the field of preparation of tea alcohol extract, achieves significant inhibitory effect and increased mRNA expression level

Inactive Publication Date: 2017-09-22
TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
View PDF1 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on whether the tea has the effect of preventing obesity

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method and application of herba ardisiae japonicae alcohol extract
  • Preparation method and application of herba ardisiae japonicae alcohol extract
  • Preparation method and application of herba ardisiae japonicae alcohol extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0022] In order to make the object, technical solution and advantages of the present invention more clear, the present invention will be further described in detail below in conjunction with the examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0023] The application principle of the present invention will be described in detail below in conjunction with the accompanying drawings.

[0024] Such as figure 1As shown, the preparation method of the ethanol extract provided by the embodiments of the present invention comprises the following steps:

[0025] S101: Preparation of Alcoholic Extract of C. chinensis: after drying and pulverizing the medicinal material of C. chinensis at low temperature, accurately weigh 0.1 g, add 0.1 mL of methanol, vortex and oscillate for 60 minutes, and then ultrasonicate for 60 minutes at a power of 200 W and a frequency of 40 kHz. Al...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and discloses a preparation method and application of a herba ardisiae japonicae alcohol extract. The preparation method comprises the following steps: after drying and crushing a herba ardisiae japonicae medicinal material at low temperature, weighing 0.1g of the crushed herba ardisiae japonicae medicinal material, and adding 0.1mL of methanol; after carrying out vortex oscillation, carrying out ultrasonic treatment and cooling; then weighing the weight, and supplementing the reduced weight with the methanol; uniformly shaking and filtering; taking subsequent filtrate and preserving for later use; weighing a bergenin reference substance, and adding the methanol to prepare a solution; determining the content of bergenin in the herba ardisiae japonicae alcohol extract by adopting an ultra-high performance liquid chromatography. According to the preparation method and the application of the herba ardisiae japonicae alcohol extract, the content of the bergenin in the herba ardisiae japonicae alcohol extract is 9.88mg / g and accords with quality standards; herba ardisiae japonicae can be used for reducing the quantity of lipid droplets in ST-2 and C3H10 cells which are obtained by inducing adipogenesis differentiation, and for inhibiting mRNA expression of adipogenesis differentiation characterization genes PPARgamma, C / EBPalpha and aP2; interventional treatment of the herba ardisiae japonicae can be used for effectively reducing the weight of C57BL / 6 mice fed by high fat diet.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a preparation method and application of an alcoholic extract of tealeaves. Background technique [0002] Obesity (OB) is a chronic metabolic disease characterized by an increase in the number and volume of adipocytes (AD) in the body, resulting in an abnormally high percentage of body fat, accompanied by excessive deposition of local adipose tissue. In recent years, with the improvement of socioeconomic level, obesity is spreading at an alarming rate among adults and adolescents all over the world, especially the trend of obesity occurring at a younger age is particularly prominent. Obesity not only reduces the quality of life of patients, but also is a common risk factor for many diseases such as diabetes, coronary heart disease, atherosclerosis, hypertension, hyperlipidemia, and tumors. The impact of obesity on human health has become a global ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/185A61P3/04C12N5/077C12Q1/02
CPCA61K36/185A61K2236/15A61K2236/33C12N5/0653C12N2500/76C12N2506/1353G01N33/5008G01N33/5073
Inventor 郑纺崔壮常艳旭王宝利王海晓陈莹
Owner TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com