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Piperacillin induced hemolysis detection reagent kit and method for preparing same

A detection kit, piperacillin technology, applied in the field of piperacillin-induced hemolysis detection kit and its preparation

Pending Publication Date: 2017-09-05
江苏中济万泰生物医药有限公司
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  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The column gel detection method has been widely used in the detection of ABO blood type, irregular antibodies in serum and cross-matching blood, but there is no relevant research report in the detection of piperacillin-induced hemolysis

Method used

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  • Piperacillin induced hemolysis detection reagent kit and method for preparing same
  • Piperacillin induced hemolysis detection reagent kit and method for preparing same
  • Piperacillin induced hemolysis detection reagent kit and method for preparing same

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Embodiment Construction

[0077] The present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments.

[0078] Such as figure 1 , figure 2 As shown, a piperacillin-induced hemolysis detection kit in the present embodiment comprises a box body 1 and a box cover 2, the bottom surface of the box body 1 is provided with an anti-skid rubber layer 3, and the box body 1 is provided with There are piperacillin-induced hemolysis detection reagent card I and piperacillin-induced hemolysis detection reagent card II, and the piperacillin-induced hemolysis detection reagent card I and piperacillin-induced hemolysis detection reagent card II both include vertical Fixed plate 4, the top of the vertical fixed plate 4 is provided with a horizontal support plate 5, and the horizontal support plate 5 is provided with a plurality of microcolumn gel tubes 6, and the microcolumn gel tubes 6 include a reaction chamber 6.1 and a gel separation column 6.2, the react...

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Abstract

The invention relates to a piperacillin induced hemolysis detection reagent kit and a method for preparing the same. The piperacillin induced hemolysis detection reagent kit comprises piperacillin inducible hemolysis detection reagent cards I, piperacillin inducible hemolysis detection reagent cards II, piperacillin treated red blood cells, non-piperacillin treated red blood cells, antibody positive control liquid and antibody negative control liquid. The piperacillin treated red blood cells are normal O Rh (rhesus) negative red blood cells treated by piperacillin medicine solution; the non-piperacillin treated red blood cells are normal O Rh negative red blood cells with the concentration of 2-2.5%; the piperacillin antibody positive control liquid is piperacillin antibody positive serum; the piperacillin antibody negative control liquid is piperacillin antibody negative serum. The piperacillin induced hemolysis detection reagent kit and the method have the advantages that the piperacillin inducible hemolysis detection reagent kit is high in sensitivity, good in repeatability and stable in quality, detection procedures are short in time consuming, the method is simple, convenient and feasible, and results are easy to judge.

Description

technical field [0001] The invention relates to a piperacillin-induced hemolysis detection kit and a preparation method thereof, which are suitable for detecting and diagnosing ongoing hemolysis caused by piperacillin treatment, predicting whether the treatment with piperacillin will cause hemolysis, and guiding clinical Reasonable choice of antibiotics. Background technique [0002] At present, the adverse reactions caused by drugs are increasing day by day, and the cases of drug-induced hemolytic anemia are also increasing year by year. If the drug is not discontinued or treated in time, the condition will be aggravated and even life-threatening. Piperacillin is the third-generation semi-synthetic penicillin, which has broad-spectrum antibacterial effect and is one of the most commonly used antibacterial drugs in clinical practice. Septicemia, respiratory tract, biliary tract and urinary system infection, subacute endocarditis and suppurative meningitis, etc. It has bee...

Claims

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Application Information

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IPC IPC(8): G01N33/15G01N33/559
CPCG01N33/15G01N33/559G01N2333/385G01N2800/52
Inventor 陈亚平吴明磊
Owner 江苏中济万泰生物医药有限公司
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