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Blood sample offering device, platelet aggregation function detector and detection method thereof

A technology for platelet aggregation and blood samples, which is applied in the field of blood sample supply devices, can solve problems such as platelet aggregation, platelet loss, and impact on platelet measurement, and achieve rapid detection, fast detection speed, and reliable detection results.

Active Publication Date: 2017-09-01
上海澜澈生物科技有限公司
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Problems solved by technology

However, the problems brought about by these two methods are: (1) red blood cell lysis, resulting in the release of ADP (adenosine diphosphate), ADP is a platelet agonist, which will promote platelet aggregation; (2) use a porous membrane to filter red blood cells, May cause potential platelet loss, affecting final platelet function measurements

Method used

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  • Blood sample offering device, platelet aggregation function detector and detection method thereof
  • Blood sample offering device, platelet aggregation function detector and detection method thereof
  • Blood sample offering device, platelet aggregation function detector and detection method thereof

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Embodiment Construction

[0059] The implementation of the present invention is described below through specific examples and in conjunction with the accompanying drawings, and those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through other different specific examples, and various modifications and changes can be made to the details in this specification based on different viewpoints and applications without departing from the spirit of the present invention.

[0060] Before introducing the present invention, first explain the principle that the present invention utilizes optical detection platelet aggregation function:

[0061] figure 1 (a) with figure 1 (b) is a schematic diagram of the principle of using optical detection of platelet aggregation function in the present invention. As shown in the figure, anticoagulant drugs and activators are ...

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Abstract

The invention discloses a blood sample offering device, a platelet aggregation function detector and a detection method thereof. The detector comprises: a blood drawing control module, which is arranged at a first air hole, a second air hole and a third air hole of the blood sample offering device; an optical detection module, which is controlled by a main control module, emits a light source on one side of a detection chamber and collects received luminous flux on the other side, converts the received luminous flux into a voltage signal, performing sampling on the voltage signal and then transmitting the signal to the main control module; and the main control module, which controls the blood drawing control module to complete on-off state control and air inflation state control of various air holes in the blood sample offering device, carries out analysis modeling on the sampled values of the optical detection module, and inverses the blood aggregation degree of platelet under the action of anticoagulation drugs. The invention a multi-channel whole blood detection system, which can reflect the efficacy of different anticoagulation drugs and a same anticoagulation drug under different dosages, and the detection speed is fast.

Description

technical field [0001] The invention relates to the field of laboratory medicine, in particular to a blood sample supply device, a platelet aggregation function detector, and a detection method thereof. Background technique [0002] Thrombotic disease refers to the general term for various diseases such as myocardial infarction and cerebral infarction caused by blood embolism. According to the data released by international and Chinese health organizations, the death rate caused by thrombosis has long occupied the first place in the death of all causes. Thrombosis has the characteristics of high mortality rate, high incidence rate, high recurrence rate, and high disability rate. The most serious disease that threatens human health and life. [0003] Platelets are an important component of blood coagulation and hemostasis. Long-term laboratory research and clinical practice have confirmed that platelets are the first and key factor in thrombus formation. Platelet function t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/59G01N1/36
CPCG01N1/36G01N21/59
Inventor 庄泉洁
Owner 上海澜澈生物科技有限公司
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