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Special drug-loading hot-melt pressure-sensitive adhesive

A hot-melt pressure-sensitive adhesive and drug-loading technology, which is applied in the field of medical materials, can solve the problems that the antibacterial effect is not optimal and the drug-loading effect is not optimal, and achieve good drug-loading effect, improve viscosity, and inhibit good effect of bacteria

Inactive Publication Date: 2017-06-23
嘉好(太仓)新材料股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the antibacterial effect of this styrene-based hot-melt pressure-sensitive adhesive has not reached the best state, and the drug-loading effect is not optimal.

Method used

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  • Special drug-loading hot-melt pressure-sensitive adhesive
  • Special drug-loading hot-melt pressure-sensitive adhesive
  • Special drug-loading hot-melt pressure-sensitive adhesive

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Embodiment Construction

[0020] The invention relates to a special hot-melt pressure-sensitive adhesive for drug loading, the components of which are: SIS thermoplastic elastomer (styrene-isoprene-styrene block copolymer) 20-30 parts, acrylic acid 1-5 parts of resin, 5-20 parts of SBS thermoplastic elastomer (styrene-butadiene-styrene block copolymer), 30-50 parts of tackifier, 10-15 parts of plasticizer, 5 parts of antibacterial agent -12 parts, 0.01-1 part of anti-aging agent and the balance of antioxidant, said tackifier is selected from polyvinylpyrrolidone and petroleum resin, rosin resin, terpene resin, terpene-styrene resin, coumarone-terpene A mixed mixture of one type of resin, wherein the polyvinylpyrrolidone accounts for more than 50% by weight of the tackifier.

[0021] In this embodiment, a mixture of SIS thermoplastic elastomer and SBS thermoplastic elastomer is used as the matrix of the hot-melt pressure-sensitive adhesive, which greatly reduces the manufacturing cost; on the basis of t...

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Abstract

The invention discloses a special drug-loading hot-melt pressure-sensitive adhesive, which is prepared from the following components in parts by weight: 20-45 parts of a styrene-isoprene-styrene block copolymer thermoplastic elastomer, 1-5 parts of acrylic resin, 5-20 parts of styrene-butadiene-styrene block copolymer thermoplastic elastomer, 20-35 parts of a tackifier, 10-15 parts of a plasticizer, 5-12 parts of a bacteriostatic agent, 0.01-1 part of an age resister and the balance of anti-oxidant, wherein the tackifier is a mixture formed by mixing polyvinylpyrrolidone and one of petroleum resin, rosin resin, terpene resin, terpene-styrene resin and coumarone-terpene resin, wherein polyvinylpyrrolidone accounts for over 50% of the weight of the tackifier. The special drug-loading hot-melt pressure-sensitive adhesive is lasting in adhesivity, good in weather resistance and heat resistance, good in antibacterial effect, good in drug-loading effect and low in cost.

Description

[0001] 【Technical field】 [0002] The invention belongs to the technical field of medical materials, in particular to a special hot-melt pressure-sensitive adhesive for drug loading. [0003] 【Background technique】 [0004] Hot-melt pressure-sensitive adhesives can produce excellent hot tack at moderately high temperatures, are solid at room temperature, and can produce good bonding effects with fingers or light pressure. Compared with ordinary hot-melt pressure-sensitive adhesives, medical hot-melt pressure-sensitive adhesives are in direct contact with the skin, so they must have the requirements of hypoallergenicity, good moisture permeability, moderate adhesion, and high drug loading. [0005] Chinese Patent No. CN201210022935.0 published on July 11, 2012 discloses a styrene-based hot-melt pressure-sensitive adhesive and its preparation method by introducing polar groups into the molecules of styrene-based thermoplastic elastomers , and with a polarity regulator to change ...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K47/32A61K36/886A61K36/896A61P31/02A61P31/04A61P17/02C09J139/06C09J153/02C09J133/00C09J11/08C09J11/06
CPCA61K9/7053A61K36/48A61K36/886A61K36/896C08L2205/025C08L2205/035C09J11/06C09J11/08C09J139/06A61K2300/00C08L53/02C08L33/00C08K5/0058
Inventor 史云霓朱志祥明丹李晓娇
Owner 嘉好(太仓)新材料股份有限公司
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