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Lactobacillus plantarum PLH1405 and application to preparation of medicine for treating acute alcoholic intoxication

A technology of PLH1405 and Lactobacillus plantarum, applied in the direction of drug combination, microbial-based methods, biochemical equipment and methods, etc., to achieve the effects of accelerating metabolism, increasing antioxidant enzyme activity, and improving dehydrogenase activity

Active Publication Date: 2017-06-20
DALIAN MEDICAL UNIVERSITY
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, so far there is no report about Lactobacillus plantarum can comprehensively promote alcohol metabolism, thereby alleviating alcoholism

Method used

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  • Lactobacillus plantarum PLH1405 and application to preparation of medicine for treating acute alcoholic intoxication
  • Lactobacillus plantarum PLH1405 and application to preparation of medicine for treating acute alcoholic intoxication
  • Lactobacillus plantarum PLH1405 and application to preparation of medicine for treating acute alcoholic intoxication

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Embodiment Construction

[0027] According to the conventional isolation method of strains, Lactobacillus plantarum PLH1405 was screened from the feces of people with high ethanol metabolism ability, and it has been preserved in the General Microbiology Center of China Committee for the Collection of Microorganisms, with the preservation number: CGMCC No.12464.

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Abstract

The invention discloses lactobacillus plantarum PLH1405. The lactobacillus plantarum PLH1405 is already collected in The China General Microbiological Culture Collection Center, has a collection number of CGMCC No. 12464, can be used for improving the activity of alcohol dehydrogenase and acetaldehyde dehydrogenase of an organism and accelerating the metabolism of alcohol and acetaldehyde, meanwhile, can be used for increasing the activity of antioxidase and reducing the generation of endotoxin, and can be used for better relieving the damage, which is brought by the alcoholic intoxication, to the organism, and is used as a medicine for treating the acute alcoholic intoxication.

Description

technical field [0001] The invention relates to a new bacterial strain and its application, especially a plant lactobacillus PLH1405 and its application in the preparation of drugs for treating alcoholism. Background technique [0002] Acute Alcohol Intoxication (Acute Alcohol Intoxication), commonly known as drunkenness, refers to a disease characterized by neuropsychiatric symptoms caused by excessive intake of ethanol in a short period of time, which can cause greater damage to the body in a short period of time, and can even cause death directly or indirectly. At present, the clinical treatment for acute alcoholism mostly adopts Western medicine, and different doses of naloxone are used according to the degree of intoxication. For critically ill patients, rapid emesis, gastric lavage, and fluid replacement are also used. The main purpose of naloxone treatment is to promote the rapid recovery of patients and relieve the inhibition of the nerve center, but it cannot solve...

Claims

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Application Information

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IPC IPC(8): C12N1/20A61K35/747A61P25/32C12R1/25
CPCA61K35/747C12N1/205C12R2001/25
Inventor 文姝唐立丁锐宁凯婷刘银辉庞立园张瑾
Owner DALIAN MEDICAL UNIVERSITY
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