Piezoelectric thin film resonator, its manufacturing method and method for detecting coagulation time

A piezoelectric film and a manufacturing method, which are applied in the field of clinical medical testing, can solve the problems of high manufacturing difficulty, large external noise, and large amount of blood samples, and achieve the effects of accurate clotting time judgment, low output noise, and easy manufacturing.

Active Publication Date: 2019-12-03
SHANDONG UNIV OF SCI & TECH
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The disadvantages of the above-mentioned technical solution are: (1) the structure of the instrument is complex and difficult to manufacture; (2) the amount of blood samples used is large, which requires special blood collection and processing, which is not suitable for home use; (3) the external The noise is large, the method of determining the coagulation time point is not reliable enough, and the test results need to be further calibrated

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Piezoelectric thin film resonator, its manufacturing method and method for detecting coagulation time
  • Piezoelectric thin film resonator, its manufacturing method and method for detecting coagulation time
  • Piezoelectric thin film resonator, its manufacturing method and method for detecting coagulation time

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0040] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments, but the present invention is not limited to these embodiments.

[0041] The piezoelectric thin film resonator used in the present invention is generally composed of a silicon substrate, a supporting film layer, a piezoelectric layer and electrodes, and its structure can be a diaphragm model, an air gap type, and a solid assembly type. In order to ensure that the thin film resonator can effectively resonate in the blood viscous environment, it is better to use a piezoelectric thin film resonator operating in the shear wave mode for the measurement of coagulation time. The electrodes of the piezoelectric thin film resonator can be arranged in parallel on the upper surface of the piezoelectric layer, or placed on both sides of the piezoelectric layer. The shape of the piezoelectric thin film resonator electrodes can be circular, square or ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
Login to view more

Abstract

The invention discloses a piezoelectric film resonator used for coagulation detection, which comprises a piezoelectric film layer and an annular groove. The invention also discloses a manufacturing method of a piezoelectric thin film resonator for blood coagulation detection, which includes coating the inner surface of the annular groove with a hydrophilic polymer material; performing oxygen plasma on the inner surface of the annular groove treatment or ultraviolet light irradiation; placing the piezoelectric thin film resonator in sodium carbonate solution, and then adding calcium chloride solution in the solution; baking the piezoelectric thin film resonator until dry. The invention also discloses a method for detecting coagulation time by using a piezoelectric thin film resonator. Calculate the second derivative of the resonance frequency with respect to the time change of the stabilized resonance frequency, and take the maximum value of the second derivative as the coagulation time. Using the piezoelectric thin film resonator to detect blood coagulation is suitable for home use.

Description

technical field [0001] The invention belongs to the field of clinical medical detection, and in particular relates to a piezoelectric thin film resonator, a manufacturing method thereof and a method for detecting coagulation time. Background technique [0002] Blood clotting time detection is one of the important routine examinations before surgery, and its clinical results indicate the risk of various thrombotic diseases or bleeding diseases. In addition, for patients using anticoagulant drugs, the test results of coagulation time are an important reference for adjusting the dosage of anticoagulant drugs. Especially for some oral anticoagulant drugs that need to be taken for a long time, such as warfarin, the anticoagulant effect varies greatly among individuals, and the interaction with other drugs is complicated, and natural food also affects its anticoagulant effect. Therefore, in order to ensure the anticoagulant effect and avoid the risk of bleeding, patients need to ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): H03H9/17H03H3/02G01N27/00
CPCG01N27/00H03H3/02H03H9/171H03H2003/023
Inventor 陈达王璟璟刘维慧王鹏苗泉
Owner SHANDONG UNIV OF SCI & TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap