Glycerin fructose sodium chloride injection and preparation method thereof
A technology of sodium chloride injection and sodium chloride, which is applied in the fields of active ingredients of alkali/alkaline earth metal chlorides, blood diseases, and pharmaceutical formulations, and can solve problems such as hidden dangers of drug use, rising content, and exceeding safety limits for patients, and achieve guaranteed The effect of product quality
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Embodiment 1
[0021] Prescription: Take 0.1kg of glycerin, 0.05kg of fructose, 0.009kg of sodium chloride, 0.0006kg of activated carbon, 0.0003kg of calcium sodium edetate, appropriate amount of citric acid, and add water for injection to 1L.
[0022] Preparation process: Weigh the raw materials and auxiliary materials according to the prescription and reserve; put glycerin and sodium chloride in a beaker, add water for injection to make the concentration of sodium chloride 4%, stir and dissolve with a glass rod, add 0.03% (W / V) Activated carbon, boil for 14 minutes, let it cool to 80℃, filter with 0.22μm microporous membrane, transfer to another beaker, add water for injection to 2L, stir evenly with a glass rod, turn on nitrogen, adjust the nitrogen pressure gauge to 0.1bar, take a sample to check the content of glycerin and sodium chloride; put calcium sodium edetate into a beaker, stir to dissolve, add fructose at 40℃, stir to dissolve with a glass rod, add 0.03% (W / V) activated carbon , U...
Embodiment 2
[0024] Prescription: Take 0.21kg of glycerin, 0.1kg of fructose, 0.018kg of sodium chloride, 0.0012kg of activated carbon, 0.0006kg of calcium sodium edetate, appropriate amount of citric acid, and add water for injection to 2L.
[0025] Preparation process: Weigh the raw materials and auxiliary materials according to the prescription and reserve; put glycerin and sodium chloride in a beaker, add water for injection to make the concentration of sodium chloride 4%, stir and dissolve with a glass rod, add 0.03% (W / V) Activated carbon, boil for 14 minutes, let it cool to 80℃, filter with 0.22μm microporous membrane, transfer to another beaker, add water for injection to 2L, stir evenly with a glass rod, turn on nitrogen, adjust the nitrogen pressure gauge to 0.1bar, take a sample to check the content of glycerin and sodium chloride; put calcium sodium edetate into a beaker, stir to dissolve, add fructose at 40℃, stir to dissolve with a glass rod, add 0.03% (W / V) activated carbon , U...
Embodiment 3
[0027] Prescription: Take 0.3 kg of glycerin, 0.15 kg of fructose, 0.027 kg of sodium chloride, 0.0012 kg of activated carbon, 0.0006 kg of calcium sodium edetate, appropriate amount of citric acid, and add water for injection to 3L.
[0028] Preparation process: Weigh the raw materials and auxiliary materials according to the prescription and reserve; put glycerin and sodium chloride in a beaker, add water for injection to make the concentration of sodium chloride 4%, stir and dissolve with a glass rod, add 0.03% (W / V) Activated carbon, boil for 14 minutes, let cool to 80°C, filter with 0.22μm microporous membrane, transfer to another beaker, add water for injection to 2L, stir evenly with a glass rod, turn on nitrogen, adjust the nitrogen pressure gauge to 0.1bar, take a sample to check the content of glycerin and sodium chloride; put calcium sodium edetate into a beaker, stir to dissolve, add fructose at 40℃, stir to dissolve with a glass rod, add 0.03% (W / V) activated carbon ...
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