3D printing device applicable to pneumatic extruding low-temperature platform control

Abstract

The invention provides a 3D printing device applicable to pneumatic extruding low-temperature platform control, and belongs to the field of tissue engineering technology and biological 3D printing technology. The 3D printing device comprises a bottom plate, a side plate, a nozzle device, a three-dimensional moving mechanism, a forming platform cooling device and a forming platform control mechanism, wherein the nozzle deice is mounted on a Z-axis slide block in a thread connection manner; the forming platform cooling device is fixedly mounted on a slide block in the forming platform control mechanism through a cap; the three-dimensional moving mechanism can realize moving in X, Y and Z directions; the forming platform cooling device can be controlled through the forming platform control mechanism to move in the X direction; and a water inlet and a water outlet are formed in the bottom part of the forming platform control mechanism. According to the 3D printing device, an extruding forming technological system is adopted; the temperature of a forming platform is controlled so as to print a scaffold tissue with high mechanical property; a method for cooling the forming platform through water circulating is carried out to ensure a low-temperature working environment for the extruding of biologic materials, and thus a solution is promoted to crosslink to form hydrogel, and as a result, the mechanical property and the integrity of a scaffold can be improved.

Description

technical field [0001] The invention belongs to the technical fields of tissue engineering technology and biological 3D printing, and relates to a 3D printing device, in particular to a 3D printing device suitable for controlling a pneumatic extrusion low-temperature platform. Background technique [0002] For the treatment of damaged large soft tissues and internal organs, the transplantation of human tissues and organs is an extremely effective treatment method. However, due to the shortage of organ donor sources, immune rejection and other problems, there are insurmountable difficulties in the practical application of organ transplantation. The proposal of tissue engineering has opened up a new way for the above problems. Tissue engineering is to attach living cells to a biomaterial matrix or a prepared scaffold by a certain method to construct a functional tissue substitute. Then the constructed tissue body substitutes are cultured and implanted into the patient's body...

AI Technical Summary

Problems solved by technology

The highest temperature of this kind of 3D printing platform can reach 135°C, which belongs to the 3D printing of metal materials. For biomass materials, the cells will die when the temperature exceeds a certain range, and the printing working environment requirements are particularly difficult to achieve.

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