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External medicine for treating tinea unguium

A technology for external medicine and onychomycosis, applied in the field of external medicine for treating onychomycosis, can solve the problems of easy re-germination, difficult to cure, easy to recur and the like

Inactive Publication Date: 2017-05-10
范暄民
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, ointments, liquid medicines, and oral drugs such as griseofulvin, terbinafine hydrochloride tablets, itraconazole, Spirano Waiting for treatment, the effect is poor after use, the cure rate is low, it is difficult to cure, and it is easy to relapse
Trace it to its cause, the side effect of oral medicine is big, can not insist on taking for a long time; External medicine is except medicine factor, because nail is a kind of compact connective tissue, the medicine penetration in the above-mentioned preparation is weak, it is difficult to enter the stratum corneum to kill or Inhibit fungal hyphae and spores, and the above preparations have weak binding force with biological tissues, easy to fall off, easy to wash off, the drug stays on the nail for a short time, does not effectively change the living environment of pathogenic bacteria, and is difficult to kill fungi directly , easy to germinate

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0026] According to the further preferred raw materials of the present invention: Scorpion 10, salicylic acid 5, ketoconazole 4, propolis 50, Speranthema 20, laurozone 2, and sesame oil 15.

[0027] Preparation:

[0028] 1. According to the conventional traditional Chinese medicine adding water decoction method, decoct twice, the first time for 30 minutes, the second time for 20 minutes, combine the filtrate, concentrate, dry, crush, pass through a 200-mesh sieve, and set aside.

[0029] 2. Put the scorpions into the sesame oil and fry them in batches, filter the oil and discard the residue, and set aside.

[0030] 3. After cooling down to 50°C in 2., add salicylic acid, ketoconazole, and laurocapram in turn, homogenize, and finally add 1. Stir evenly, and keep at 45°C for later use.

[0031] 4. Put the propolis in a 70°C incubator for 3-4 hours. When it becomes a thin paste, add 3., stir well, and cool to a hard paste, which is this product.

[0032] Instructions:

[0033]...

example 1

[0036] On June 23, 2011, Wang X X, female, 49 years old, a farmer, suffered from fungal leuconychia on both big toes for three years. The ointment and tincture used to treat onychomycosis had no effect, and the drug of the embodiment was used for one and a half courses of treatment Grow new nails. One year later, there was no recurrence.

[0037] case two

[0038] On September 10, 2013, Liu X X, male, 52 years old, a worker, had suffered from onychomycosis for many years. His nails were gray, thickened, and deformed. Use the embodiment medicament, and new nail grows out after two courses of treatment. One year later, there was no recurrence.

[0039] case three

[0040] On August 19, 2014, Zhao X, female, 53 years old, a retired worker, suffered from onychomycosis on both thumbs and index fingers for five years. The nails were gray, thickened, and deformed, which affected the appearance. I used ointment and tincture to treat onychomycosis, but the effect was not obvious, ...

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PUM

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Abstract

The invention discloses an external medicine for treating tinea unguium. The external medicine comprises, by weight, 1-10 parts of scorpio, 1-5 parts of salicylic acid, 1-8 parts of ketoconazole, 40-70 parts of propolis, 15-40 parts of herba speranskiae tuberculatae, 1-5 parts of laurocapram and 15-30 parts of sesame oil. The external medicine for treating the tinea unguium has the advantages that the external medicine is high in adhesion and cure rate, durable in efficacy and free of irritation and can be permeated into stratum corneum to kill fungi, and accordingly good treatment effects can be realized.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to an external medicine for treating onychomycosis. Background technique [0002] Onychomycosis, Chinese medicine is called chicken feet, putty nails, Western medicine is called onychomycosis, refers to the disease caused by dermatophytes invading the nail plate or under the nail. Onychomycosis is a nail infection caused by fungi such as dermatophytes, yeasts, and nondermatophytes. Two common types of onychomycosis: ① fungal leucoonychia (superficial white onychomycosis) This type of lesion is limited to a piece of the nail surface or its tip; ② Subungual mycosis is divided into distal lateral type and proximal nail Inferior type and superficial white type, this type of lesion starts from both sides or the distal end of the nail, and then the infection occurs under the nail plate. [0003] Onychomycosis is a stubborn skin disease. At present, ointments, liqu...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K36/47A61P17/00A61P31/10A61K35/646A61K31/55A61K31/60A61K31/496A61K35/644
Inventor 范暄民
Owner 范暄民
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