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Radiofrequency treatment system

A treatment system and radio frequency technology, applied in medical science, surgery, parts of surgical instruments, etc., can solve the problems of tumor diagnosis, slow drug treatment, slow action, etc., achieve good therapeutic effect, less normal tissue damage, fully functional effects

Inactive Publication Date: 2017-04-05
BEIJING FUNAKANG BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the existing treatment methods targeting tumor blood vessels are usually relatively slow drug administration, and tumor angiogenesis inhibitors are only suitable for early tumors, but usually early tumor diagnosis itself is a difficult problem
Tumor blood vessel blocking agents have relatively good effects, but they act slowly and have certain side effects

Method used

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Examples

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Effect test

Embodiment 1

[0034] Example 1. Radiofrequency Therapy System for Targeting Tumor Vascular Therapy

[0035] The radio frequency treatment system for targeted tumor blood vessel treatment of the present invention includes nanometer material and radio frequency device; the radio frequency signal emitted by the radio frequency device causes the nanometer material in the tumor blood vessel to move and destroy the blood vessel, thereby treating the tumor.

[0036] Specifically, the nanomaterials can be water-soluble Gd metal fullerene nanoparticles (Gd@C 82 (OH) n ), through the following steps for Gd@C 82 Water-soluble modification: Weigh 100mg Gd@C 82 Solid (purchased from Xiamen Funa New Material Technology Co., Ltd.), 7mL of 30% hydrogen peroxide, 3mL of 10% sodium hydroxide, reacted at 50°C until the powder was completely dissolved, then washed with ethanol, dialyzed to obtain metal Fullerene hydroxylated derivatives (Gd@C 82 (OH) n ) in aqueous solution.

[0037] After the above-ment...

Embodiment 2

[0040] Embodiment 2, using the radiofrequency treatment system of the present invention to treat tumors

[0041] 1. Establishment of tumor model

[0042] The invention establishes various tumor models, including H22 mouse liver cancer model, 4T1 mouse breast cancer model, HeLa human cervical cancer model and the like. All cell beads used were purchased from Concord Cell Resource Center.

[0043] The specific establishment process is as follows:

[0044] ①The H22 mouse liver cancer model is formed by inoculating the ascites of mice to form tumors. The specific steps are as follows: Passage the H22 ascites passaged from Kunming mice to form a certain number of ascites, that is, cells, then absorb the ascites, wash away the impurities in the ascites with PBS, and then inoculate To the subcutaneous position of the right hind limb of Bal / bC mice, the number of inoculated cells is about 5*10^6, and then grown for 6-7 days before use.

[0045] ② 4T1 mouse breast cancer model and H...

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Abstract

The invention discloses a radiofrequency treatment system. The radiofrequency treatment system for target tumor vessel treatment comprises nano materials and a radiofrequency instrument. A radiofrequency signal transmitted by the radiofrequency instrument enables the nano materials enriched in a tumor vessel to move to damage the tumor vessel, and therefore tumors are treated. Or, by means of the radiofrequency signal transmitted by the radiofrequency instrument, the intake of the nano materials at the tumor positions can be improved, the interaction of the nano materials and the tumors can be increased, and the curative effect of tumor treatment can be improved. The radiofrequency treatment system is simple in instrument and equipment and complete in function, treatment and defection are effectively combined, the adjustable range is wide, the adjusted frequency range can reach 50 MHz to 500 MHz, the power can reach 0 W to 100 W, and the good function and effect are achieved on tumor treatment; and multiple kinds of tumors can be treated, the radiofrequency treatment system is suitable for small animals and large animals and can be applied to human cancer treatment through coil parameter changing, and great prospects are achieved.

Description

technical field [0001] The invention relates to the field of biomedicine and the field of radio frequency coils, in particular to a radio frequency treatment system for targeting tumor blood vessels. Background technique [0002] Cancer has become a major killer that threatens human life and health. Many people lose their lives due to cancer every year, so the treatment of cancer is imminent. At present, the traditional methods of treating cancer mainly include surgical treatment, radiotherapy, and chemical drug treatment, but there are certain defects in the traditional treatment methods. For example, surgical treatment is to remove tumor tissue through surgery, but it is difficult to remove all tumor cells, so it is not applicable Radiation therapy is easy to damage normal cells, easy to transfer; chemical drug therapy uses drugs to act on tumors, which is easy to cause drug resistance and so on. Therefore, some new tumor treatment methods have also been developed, such a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B18/18
CPCA61B18/18
Inventor 王春儒李雪甄明明
Owner BEIJING FUNAKANG BIOTECH CO LTD
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