Injectable in-situ gel capable of replacing surgical catgut for acupuncture and moxibustion embedding
A technology of in-situ gel and catgut, which is applied in the directions of non-active ingredients medical preparations, medical preparations containing active ingredients, organic active ingredients, etc., can solve the problems of limited toxic and side effects, low bioavailability, etc.
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Embodiment 1
[0117] Composition: PLGA 30g, HMPC 2g, PEG400 10g and NMP 54g.
[0118] Process: After mixing PEG400 and NMP, add HPMC, after complete mixing, add PLGA, vortex shake for 24 hours, sterilize with Co60, and store in the dark at 4°C to obtain the product.
[0119] Usage and dosage: acupoint injection; dosage: 16mg once for adults; dosing interval: once a week.
Embodiment 2
[0121] Composition: PLGA 45g, HMPC 3g, PEG400 20g and NMP 65g.
[0122] Process: After mixing PEG400 and NMP, add HPMC, after complete mixing, add PLGA, vortex for 28 hours, sterilize with Co60, and store in the dark at 4°C to obtain the product.
[0123] Usage and dosage are the same as in Example 1.
Embodiment 3
[0125] Composition: PLGA 15g, HMPC 1g, PEG400 1g and NMP 40g.
[0126] Process: After mixing PEG400 and NMP, add HPMC, and after mixing completely, add PLGA, vortex for 20 hours, sterilize with Co60, and store in the dark at 4°C.
[0127] Usage and dosage are the same as in Example 1.
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