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Injectable cosmetic and plastic material and preparation method thereof

A technology for injection and water for injection, applied in the field of materials, can solve the problems of tissue induration and insufficient mechanical strength, and achieve the effect of soft tissue, eliminating wrinkles and depressions

Active Publication Date: 2017-03-15
BEIJING ALLGENS MEDICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] The technical problem to be solved by the present invention is to provide an injectable cosmetic plastic material for the insufficient mechanical strength of existing filling materials and the problem of induration in the injected tissue. The material provided by the present invention has high mechanical strength , Bone formation can be seen after injection, and the most natural effect can be achieved after injection, with soft tissue and no induration

Method used

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  • Injectable cosmetic and plastic material and preparation method thereof
  • Injectable cosmetic and plastic material and preparation method thereof
  • Injectable cosmetic and plastic material and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] The collagen sponge was pulverized into powder with a pulverizer, the speed of the pulverizer was set at 7000rpm, and the time was set at 2s to obtain collagen powder.

[0067] The used spherical hydroxyapatite powder with a particle size of 30 μm and the collagen powder prepared in the above steps are sterilized by cobalt 60 radiation to ensure the sterility of the raw materials.

[0068] Disassemble some parts of the reaction kettle that are in contact with the product, wrap them separately with the scissors, tweezers, wrench, etc. used for preparation, and affix them with moist heat sterilization instructions, put them in a steam sterilizer, and sterilize with moist heat at 120°C for 30 minutes.

[0069] Add 40g of sterilized collagen powder in 4 times and 1000mL of sterile water for injection alternately into the reactor until the addition is complete, seal the reactor, start stirring at a speed of 120r / min, stir and react for 24 hours, and start at the same time Ul...

Embodiment 2

[0072] The collagen sponge was pulverized into powder with a pulverizer, the rotating speed of the pulverizer was set at 8000rpm, and the time was set at 2s to obtain collagen powder.

[0073] The used spherical hydroxyapatite powder with a particle size of 35 μm and the collagen powder prepared in the above steps were sterilized by cobalt 60 radiation to ensure the sterility of the raw materials.

[0074] Disassemble some parts of the reaction kettle that are in contact with the product, wrap them separately with the scissors, tweezers, wrench, etc. used for preparation, and affix them with moist heat sterilization instructions, put them in a steam sterilizer, and sterilize with moist heat at 120°C for 30 minutes.

[0075] Add 50g of sterilized collagen powder and 950mL of sterilized water for injection into the reaction kettle alternately in batches until the addition is complete, seal the reaction kettle, start stirring at a speed of 120r / min, stir and react for 24 hours, an...

Embodiment 3

[0078] The collagen sponge is pulverized into powder with a pulverizer, the rotating speed of the pulverizer is set at 12000rpm, and the time is set at 1s to obtain collagen powder.

[0079] The used spherical hydroxyapatite powder with a particle size of 40 μm and the collagen powder prepared in the above steps were sterilized by cobalt 60 radiation to ensure the sterility of the raw materials.

[0080] Disassemble some parts of the reaction kettle that are in contact with the product, wrap them separately with the scissors, tweezers, wrench, etc. used for preparation, and affix them with moist heat sterilization instructions, put them in a steam sterilizer, and sterilize with moist heat at 120°C for 30 minutes.

[0081] Add 50ml of lidocaine into 950ml of sterilized water for injection to form a first solution. Add 40g of sterilized collagen powder and the first solution alternately to the reactor until the addition is complete, seal the reactor, start stirring at a speed of...

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Abstract

The invention relates to an injectable cosmetic and plastic material and a preparation method thereof. Specifically, the injectable cosmetic and plastic material provided by the invention comprises collagen powder and spherical hydroxyapatite with the particle size of 30-40mum. Since the spherical hydroxyapatite with the particle size of 30-40mum is adopted, the irritation to tissues is reduced to the lowest level due to the surface smoothing feature of the spherical hydroxyapatite; more importantly, after circular and smooth microspheres are injected, the most natural effect can be achieved, tissues at an injected position are soft and have no induration. In addition, due to the particle size of the microspheres, a filling agent can be ensured to be easily injected into skin by a small needle, the microspheres can be ensured not to be swallowed and taken away by monocytes, macrophages and so on of a human body, the microspheres enduringly stay at a treated position, and the microspheres can form bones after being injected. Therefore, the mechanical strength is higher.

Description

technical field [0001] The invention relates to the field of material technology, in particular to an injectable cosmetic plastic material and a preparation method thereof. Background technique [0002] In today's society, plastic surgery is not only a patent in the field of damage repair, but also a means for people to pursue beauty. With the improvement of living standards and the development of plastic surgery technology, the way to obtain beauty through plastic surgery has gradually been accepted and trusted by people. The people receiving plastic surgery have also spread from entertainment stars engaged in performing arts to ordinary people. From the huge demand market for plastic surgery materials, we can predict their good development prospects. [0003] Various methods of plastic surgery are springing up like bamboo shoots after the rain, including traditional plastic surgery, microsurgery, skin expansion technology and injection transplantation technology, etc. Amo...

Claims

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Application Information

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IPC IPC(8): A61L27/24A61L27/12A61L27/54A61L27/58
CPCA61L27/12A61L27/24A61L27/54A61L27/58A61L2300/402A61L2400/06A61L2430/34
Inventor 何志敏张华朱金亮宋天喜仇志烨李洪景崔菡崔福斋
Owner BEIJING ALLGENS MEDICAL SCI & TECH
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