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Nano-silver antibacterial spray for treating dermatophytosis, preparation method and application

A nano-silver antibacterial and nano-silver technology, which is applied in antifungal agents, aerosol delivery, medical preparations of non-active ingredients, etc., can solve the problems that cannot be made into water-soluble preparations, drugs cannot be fully utilized, and there is no nano-silver Silver antibacterial agents and other issues, to achieve long-acting antifungal drug resistance, eliminate beriberi bacteria, and not produce drug resistance

Inactive Publication Date: 2017-03-15
SHANGHAI NAT ENG RES CENT FORNANOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There are many medicines for treating beriberi, but there are some disadvantages: Western antifungal medicines are generally insoluble in water and alcohol, and cannot be made into water-soluble preparations, and made into ointments are not conducive to skin absorption, and the medicines cannot be fully utilized
At present, there is no relevant report on the application of nano-silver antibacterial agent in beriberi spray products

Method used

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  • Nano-silver antibacterial spray for treating dermatophytosis, preparation method and application
  • Nano-silver antibacterial spray for treating dermatophytosis, preparation method and application
  • Nano-silver antibacterial spray for treating dermatophytosis, preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] (1) The nano-silver colloidal dispersion is prepared from the following raw material components by weight percentage:

[0027]

[0028] (2) The nano-silver antibacterial anti-beriberi spray can be prepared by mixing the following raw material components according to weight percentage:

[0029]

[0030] Antibacterial performance test: According to the 2002 edition of "Disinfection Technical Specifications", the antibacterial performance test is carried out. The test results show that the killing rate of the above-mentioned nano-silver antibacterial anti-beriberi spray on Candida albicans (ATCC 10231 type) is greater than 80%.

Embodiment 2

[0032] (1) The nano-silver colloidal dispersion is prepared from the following raw material components by weight percentage:

[0033]

[0034] (2) The nano-silver antibacterial anti-beriberi spray can be prepared by mixing the following raw material components according to weight percentage:

[0035]

[0036] Antibacterial performance test: According to the 2002 edition of "Disinfection Technical Specifications", the antibacterial performance test is carried out. The test results show that the killing rate of the above-mentioned nano-silver antibacterial anti-beriberi spray on Candida albicans (ATCC 10231 type) is greater than 80%.

Embodiment 3

[0038] (1) The nano-silver colloidal dispersion is prepared from the following raw material components by weight percentage:

[0039]

[0040] (2) The nano-silver antibacterial anti-beriberi spray can be prepared by mixing the following raw material components according to weight percentage:

[0041]

[0042] Antibacterial performance test: According to the 2002 edition of "Disinfection Technical Specifications", the antibacterial performance test is carried out. The test results show that the killing rate of the above-mentioned nano-silver antibacterial anti-beriberi spray on Candida albicans (ATCC 10231 type) is greater than 90%.

[0043] The spray can be used to treat tinea manuum, tinea pedis, tinea corporis, etc., without irritation and damage to the skin, and is safe and non-toxic. Generally, after 3~7 days of continuous use of this product, the itching can be relieved, and the development of beriberi symptoms can be further controlled to achieve the purpose of st...

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PUM

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Abstract

The invention discloses a nano-silver antibacterial spray for treating dermatophytosis, a preparation method and application. The spray is prepared by mixing, by weight, 0.1%-3% of skin moisturizer, 0.005%-0.05% of nano-silver sol dispersion liquid and water added to reach 100%. The product spray is colorless, transparent, high in stability and good in antibacterial / bacteriostatic performance, and the pH is controlled to range from 6 to 8. According to the spray, no organic antibacterial agent is added, and nano-silver serves as an antibacterial / bacteriostatic agent instead; besides, the spray has the effects of resisting bacteria, diminishing inflammation and quickening repair of damaged skin; moreover, the spray has a quite strong broad-spectrum bacteriostatic and bactericidal effect and can resist fungi lastingly without generating drug tolerance. The spray for treating dermatophytosis can be conveniently sprayed after being shaken; besides, the spray can relieve itching and eliminate pathogenic bacteria causing dermatophytosis to achieve the purpose of curing dermatophytosis and save the trouble of foot itching, rotting and festering.

Description

technical field [0001] The invention relates to the technical field of beriberi water, in particular to a nano-silver antibacterial spray for treating beriberi and its preparation and application. Background technique [0002] Athlete's foot, commonly known as Hong Kong's athlete's foot, is a fungus that causes beriberi. The main fungi that cause beriberi include Trichophyton rubrum, Trichophyton flocculus or Candida albicans. Although athlete's foot is a fungal infection, it can be divided into different types according to symptoms, such as papule and scales, hyperkeratosis, blisters, and interdigital erosions. [0003] There are many medicines for the treatment of beriberi, but there are some disadvantages: Western antifungal medicines are generally insoluble in water and alcohol, and cannot be made into water-soluble preparations, and made into ointments are not conducive to skin absorption, and the medicines cannot be fully utilized. Moreover, if this kind of medicine i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/12A61K33/38A61K47/18A61K47/46A61K47/42A61P17/00A61P31/10
CPCA61K47/183A61K47/42A61K47/46A61K9/0014A61K9/12A61K33/38
Inventor 何丹农林琳张春明金彩虹
Owner SHANGHAI NAT ENG RES CENT FORNANOTECH
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