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Traditional Chinese medicine compositon, nose drop containing same and application thereof

A technology of composition and medicine, which is applied in the field of traditional Chinese medicine composition and nasal drops, and can solve the problems of rapid heart rate, large side effects, pungent smell, etc.

Inactive Publication Date: 2017-01-18
INST OF TROPICAL BIOSCI & BIOTECH CHINESE ACADEMY OF TROPICAL AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, naphazoline hydrochloride nasal drops, which are common in the market and have relatively good effects, can easily cause rebound nasal congestion and drug-induced rhinitis after frequent use. Side effects such as dryness, headache, dizziness, and rapid heart rate are relatively large
The existing treatment method of oral Chinese medicine, traditional Chinese medicine rarely has side effects, but the short-term effect is not ideal, and it is difficult to relieve symptoms
There are also traditional Chinese medicine nasal drops on the market, such as Bitongning nasal drops, which are mainly used to treat nasal congestion, with single effects and pungent

Method used

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  • Traditional Chinese medicine compositon, nose drop containing same and application thereof
  • Traditional Chinese medicine compositon, nose drop containing same and application thereof

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preparation example Construction

[0039] The present invention also provides the preparation method of above-mentioned Chinese medicine nasal drop, comprises the following steps:

[0040] ①, according to the following ratio to take the composition of the raw materials mixed:

[0041] Cocklebur 1~5 parts

[0042] Mint 1~4 parts

[0043] ②, adding water to the composition for reflux extraction; filtering, and concentrating the filtrate under reduced pressure;

[0044] ③. Take agarwood, add ethanol for ultrasonic extraction; filter, concentrate under reduced pressure to remove ethanol;

[0045] ④. Add the agarwood extract obtained in ③ to the concentrated solution obtained in ②, and mix well to obtain the traditional Chinese medicine nasal drops. Preferably, the amount of water added in step ② is 5-10 times the volume of the composition; the reflux extraction is performed 2-3 times, each time is 40min-70min, and the filtrates are combined.

[0046] Preferably, the concentration under reduced pressure in step ...

Embodiment 1

[0052] Weigh 100g cocklebur and 100g peppermint, add to 1000g water and reflux extract twice, 60min each time. Filtrate and combine the filtrates; concentrate the filtrate to 50 g under reduced pressure at 50°C. Weigh 200 g of agarwood, add it to 200 mL of 95% ethanol solution, ultrasonically extract twice, 50 min each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure at 40°C until there is no ethanol. Remove the ethanol under reduced pressure, add the obtained agarwood extract into 100 g of concentrated Chinese medicine, mix well, and obtain Chinese medicine nasal drops.

Embodiment 2

[0054] Weigh 400g of agarwood, add it to 400mL of 95% ethanol solution, ultrasonically extract twice, 60min each time, filter, combine the filtrates, remove ethanol under reduced pressure, and obtain agarwood extract. Weigh 500g cocklebur and 400g mint, add to 9000g water and reflux extract twice, 70min each time. Filtrate and combine the filtrates; concentrate the filtrate to 1800 g under reduced pressure at 60°C. Add the extract of agarwood to the concentrated solution, mix well, and it will be the traditional Chinese medicine nasal drops.

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Abstract

The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition, a nose drop containing the same and application thereof. The traditional Chinese medicine nose drop is made of, by weight, 2-4 parts of agarwood, 1-5 parts of xanthium sibiricum and 1-4 parts of mint. The traditional Chinese medicine nose drop not only has effects of antisepsis and anti-inflammation and nasal mucosa protection, but also has effects of calming the nerves and relieving fatigue, and has fewer side effects.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition, nasal drops containing the traditional Chinese medicine composition and applications thereof. Background technique [0002] Rhinitis is inflammation of the nasal mucosa and submucosal tissues, manifested as congestion or edema. Patients often have symptoms such as nasal congestion, runny nose, itchy nose, throat discomfort, coughing, and sneezing. It is caused by chronic or acute nasal mucosal infection such as virus, bacterial infection or irritation. Prolonged treatment may even lead to nasal cancer. Some patients with rhinitis have hypertrophy of the inferior turbinate and lack of oxygen during sleep. In severe cases, it may cause cerebral infarction, high blood pressure, sudden heart attack, and even sudden death. About 300 million people in China are troubled by rhinitis. [0003] At present, western medicine is mostly...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/835A61P25/20A61P39/00A61P11/02A61P31/04A61P29/00
CPCA61K9/0043A61K9/08A61K36/28A61K36/534A61K36/835A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 陈惠琴杨锦玲梅文莉戴好富
Owner INST OF TROPICAL BIOSCI & BIOTECH CHINESE ACADEMY OF TROPICAL AGRI SCI
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