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Protein concentration system and application method thereof

An application method, protein technology, applied in the field of protein concentration, can solve the problems of high cost, poor reliability, high energy consumption, etc., and achieve the effect of stable and reliable heat exchange, stable heat exchange, and high energy efficiency

Active Publication Date: 2017-01-11
TECHNICAL INST OF PHYSICS & CHEMISTRY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] An object of the present invention is to provide a high-efficiency, environment-friendly, stable and reliable protein freeze-concentration system to solve the problems of high energy consumption, poor reliability and high cost in the existing freeze-drying protein freeze-concentration technology

Method used

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  • Protein concentration system and application method thereof
  • Protein concentration system and application method thereof

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Experimental program
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Effect test

Embodiment 1

[0033] Embodiment 1 Protein Solution Freeze Concentration System

[0034] A protein solution freeze concentration system, such as figure 1 and figure 2 As shown, the system includes a compressor 1 , a liquid inlet tank 3 , a heat exchange system 4 , a throttle valve 5 , a liquid storage tank 7 , and a condenser 9 . The heat exchange system 4 contains at least two honeycomb heat exchangers 4^, each honeycomb heat exchanger 4^ is arranged in parallel at intervals, at the same height, and contains refrigerant; one side of the liquid inlet tank 3 is provided with a liquid inlet 2, The bottom is provided with a round hole, which communicates with the upper part of each honeycomb heat exchanger 4^ through the round hole; the lower part of each honeycomb heat exchanger 4^ communicates with the liquid storage tank 7; the heat exchange system 4 also It communicates with the compressor 1 and the condenser 9 , and a throttling valve 5 is set between the heat exchange system 4 and the ...

Embodiment 2

[0036] Embodiment 2 Application method of a protein solution freeze concentration system

[0037] An application method of a protein solution freeze concentration system, such as figure 1 and figure 2 shown, including the following steps:

[0038] S1. The protein solution to be concentrated enters the liquid inlet tank 3 from the liquid inlet 2;

[0039] The protein solution obtained by S2 and S1 flows through the round hole at the bottom of the liquid inlet tank 3 from top to bottom under the action of gravity on one side of the honeycomb heat exchanger 4^, and passes through the other side of the honeycomb heat exchanger 4^. Compressor 1, throttling valve 5 and condenser 9 are processed to obtain low-temperature and low-pressure wet steam refrigerant for heat exchange, so that the moisture in the protein solution freezes and becomes liquid ice that remains on the wall of the honeycomb heat exchanger 4^ superior;

[0040] The concentrated protein solution obtained in S3 ...

Embodiment 3

[0045] Embodiment 3 Application method of a protein solution freeze concentration system

[0046] An application method of a protein solution freeze concentration system, such as figure 1 and figure 2 shown, including the following steps:

[0047] S1. The protein solution to be concentrated enters the liquid inlet tank 3 from the liquid inlet 2;

[0048] The protein solution obtained by S2 and S1 flows through the round hole at the bottom of the liquid inlet tank 3 from top to bottom under the action of gravity on one side of the honeycomb heat exchanger 4^, and passes through the other side of the honeycomb heat exchanger 4^. Compressor 1, throttling valve 5 and condenser 9 are processed to obtain low-temperature and low-pressure wet steam refrigerant for heat exchange, so that the moisture in the protein solution freezes and becomes liquid ice that remains on the wall of the honeycomb heat exchanger 4^ superior;

[0049] The concentrated protein solution obtained in S3 ...

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Abstract

The invention discloses a protein concentration system which comprises a compressor, a liquid inlet tank, a heat exchange system, a throttling valve, a liquid storage tank and a condenser, wherein the heat exchange system at least comprises two honeycomb heat exchangers; the liquid inlet tank is provided with a liquid inlet port, the bottom is provided with a circular hole, and the liquid inlet tank communicates with the upper part of each honeycomb heat exchanger through the circular hole; the lower part of each honeycomb heat exchanger communicates with the liquid storage tank; the heat exchange system also communicates with the compressor and the condenser; the throttling valve is arranged between the heat exchange system and the condenser; and the condenser communicates with the compressor. The invention also discloses an application method of the protein concentration system. The water in the protein solution is separated out in the form of ice slurry, so the system disclosed by the invention has the advantages of stable and reliable heat exchange and favorable concentration effect. Compared with the existing protein freeze concentration system, the system disclosed by the invention has the advantages of simple structure, stable heat exchange, high stability, high energy efficiency and the like.

Description

technical field [0001] The invention relates to the technical field of protein concentration. More specifically, it relates to a protein concentration system and its application method. Background technique [0002] In order to obtain high-concentration or high-activity proteins, protein extraction and protein separation and purification are generally connected through the concentration of protein solutions, thereby increasing protein concentration, reducing sample volume, and facilitating further purification. Based on various physical and chemical properties of proteins, commonly used protein concentration methods include precipitation, adsorption, ultrafiltration, and freeze-drying. Among them, the freeze-drying method is to freeze the protein solution at a low temperature, then sublime and dry it under vacuum conditions to remove ice crystals, and then perform analysis and drying after the sublimation is completed to remove part of the bound water, and finally achieve t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07K1/14
CPCC07K1/14Y02P20/10
Inventor 张振涛周靖轩杨鲁伟张冲魏娟杨俊玲
Owner TECHNICAL INST OF PHYSICS & CHEMISTRY - CHINESE ACAD OF SCI
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