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Traditional Chinese medicine composition and preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine and natural medicine, can solve problems such as pain, inflammatory exudation treatment that has not been paid attention to, unclear effective substances, and difficult quality control, so as to achieve safe and reliable drug sources and shorten extraction time. Time, the effect of improving extraction efficiency

Inactive Publication Date: 2016-12-14
覃淑兰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the treatment of acute paronychia is mostly treated with iodine or various antibiotics, the main purpose is to kill bacteria, but the treatment of pain, inflammatory exudation, and hyperplasia of granulation tissue has not been paid attention to.
Most of the traditional Chinese medicines are made into compound Chinese medicine preparations on the basis of ancient prescriptions or proven prescriptions, or are directly coated with single Chinese medicines. Defects such as clear, difficult to carry out quality control, inconvenient to carry

Method used

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  • Traditional Chinese medicine composition and preparation method and application thereof
  • Traditional Chinese medicine composition and preparation method and application thereof
  • Traditional Chinese medicine composition and preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0026] The preparation of embodiment 1 cactus extract 1

[0027] Take fresh cactus thorns, wash, mash, take 10kg mashed material, add pure water 8 times the weight of the mashed material, leaching in a water bath at 90°C for 3 hours, filter to obtain the filtrate, repeat the extraction 3 times, and combine the 3 filtrates for rotary evaporation Concentrate, stop concentrating when concentrated to 1 / 3 of the original extract, add ethanol with a volume percentage concentration of 95% to the concentrated solution, stir until the volume percentage concentration of ethanol is 70%, and then stand at 4°C for 16 hours , collect the precipitate by centrifugation, and dry it in vacuum at 70°C to obtain the cactus extract;

[0028] The content of the cactus polysaccharide is determined by the phenol-sulfuric acid method, and the percentage by weight of the cactus polysaccharide is 30.5% based on the weight of the cactus extract.

Embodiment 2

[0029] The preparation of embodiment 2 cactus extract 2

[0030] Take fresh cactus thorns, wash, mash, take 10kg of mashed material, add pure water 10 times the weight of the mashed material, leaching in a water bath at 100°C for 1 hour, filter to obtain the filtrate, repeat the extraction twice, and combine the two filtrates for rotary evaporation Concentrate, stop concentrating when concentrated to 1 / 5 of the original extract, add 95% ethanol to the concentrated solution, stir until the ethanol volume percent concentration is 70%, then stand at 8°C for 18 hours, Collect the precipitate by centrifugation, and dry it in vacuum at 70°C to obtain the cactus extract;

[0031] The content of the cactus polysaccharide is determined by a phenol-sulfuric acid method, and calculated based on the weight of the cactus extract, the percentage by weight of the cactus polysaccharide is 38.7%.

Embodiment 3

[0032] The preparation of embodiment 3 salvia miltiorrhiza extract 1

[0033] Salvia miltiorrhiza was crushed through a 40-mesh sieve, 10kg of the crushed product was taken, and an ethanol solution 5 times the weight of the crushed product was added to extract for 30 minutes under ultrasonic conditions. The frequency of the ultrasonic wave was 70 Hz, and the volume percentage concentration of the ethanol solution was 70%. , repeated extraction 3 times, combined 3 extractions for distillation and concentration, stopped concentration when the concentrated solution was 1 / 3 times of the original leaching solution, added 12 times the volume of the concentrated solution and washed it with 8% sodium carbonate solution for 5 times, each time Stir for 3 minutes, filter and dry to obtain the salvia miltiorrhiza extract;

[0034]Taking tanshinone I, tanshinone IIA, dihydrotanshinone, and cryptotanshinone as reference substances, and calculating based on the weight of the salvia miltiorrh...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine and natural drugs, and relates to a traditional Chinese medicine composition and a preparation method thereof. The traditional Chinese medicine composition is prepared from an opuntia extract, a salvia extract and a creeping oxalis extract with the weight ratio being 1:(0.5-2.5):(1-3). The traditional Chinese medicine composition can have the remarkable effect on the aspects of bacterium resistance, inflammation resistance, pain easing and the like. According to the action mechanism and activity strength of the traditional Chinese medicine composition, acute paronychia can be treated from the aspects of resisting bacteria, relieving swelling and pain, reducing inflammatory exudation, improving granulation tissue proliferation, and the curative effect is exact.

Description

【Technical field】 [0001] The invention belongs to the technical field of traditional Chinese medicine and natural medicine, and in particular relates to a traditional Chinese medicine composition for treating acute paronychia and a preparation method thereof. 【Background technique】 [0002] Paronychia refers to the suppurative infection of the soft tissue around the (toe) nail, which is caused by bacteria invading the subcutaneous layer through the small damage of the paraungual skin and multiplying. , Even the nail groove forms abscess and subungual empyema. Ditch inflammation is mostly caused by punctures, abrasions, ingrown nails or pulling out "inverted skin thorns" in the nail ditch and its nearby tissues. Clinically, paronychia can be divided into 4 phases, namely redness phase, inflammation phase, granulation phase, and chronic ingrown paronychia phase. Paronychia has the characteristics of high incidence and high recurrence rate. If acute paronychia cannot be treat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61P17/00A61P31/04
CPCA61K36/33A61K36/185A61K36/537A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 覃淑兰
Owner 覃淑兰
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