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Medicine compound for treating proventriculitis of broiler chicken and preparation method thereof

A composition and a technique for glandular gastritis, applied in the field of pharmaceutical composition for treating broiler glandular gastritis and its preparation, can solve the problems of increasing bacterial resistance and antibiotic residues, and achieve inhibition of gastric acid secretion, no drug residues, and therapeutic effect high effect

Inactive Publication Date: 2016-12-07
DALIAN NATIONALITIES UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the prevention and treatment of chicken glandular gastritis is mainly based on antibiotics, but with the use of antibiotics, it has caused huge side effects, resulting in a large number of antibiotic residues and increased bacterial resistance

Method used

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  • Medicine compound for treating proventriculitis of broiler chicken and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] The pharmaceutical composition for treating broiler glandular gastritis comprises 85wt% of traditional Chinese medicine extract, 5wt% of lysine, 6wt% of methionine and 4wt% of vitamin A.

[0036] The traditional Chinese medicine extract includes 1 part of Poria cocos, 15 parts of sea octopus, 20 parts of gardenia, 10 parts of Magnolia officinalis, 5 parts of betel nut, 8 parts of bletilla striata, 25 parts of Cortex Phellodendri, 15 parts of pinellia, and 15 parts of astragalus in parts by weight. , 8 angelica.

[0037] The preparation method of this pharmaceutical composition, the steps are as follows:

[0038] S1 prepares the Chinese medicine extract;

[0039] S1.1 Pulverize Poria cocos, sea octopus, and betel nut, and extract with 10 times the mass of 80% ethanol under reflux. After the ethanol is recovered from the extract, it is extracted with ethyl acetate under reflux. The ethyl acetate is recovered and dried under reduced pressure to obtain Chinese medicine ext...

Embodiment 2

[0045] The medicinal composition for treating broiler glandular gastritis comprises 90wt% of traditional Chinese medicine extract, 3wt% of lysine, 3wt% of methionine, and the balance of vitamin b2 and vitamin b6.

[0046] The traditional Chinese medicine extract includes 3 parts of Poria cocos, 12 parts of sea octopus, 15 parts of gardenia, 8 parts of Magnolia officinalis, 3 parts of betel nut, 10 parts of bletilla striata, 20 parts of Phellodendron phellodendri, 16 parts of pinellia, and 10 parts of astragalus in parts by weight. , 9 parts of angelica.

[0047] The preparation method of this pharmaceutical composition, the steps are as follows:

[0048] S1 prepares the Chinese medicine extract;

[0049] S1.1 Pulverize Poria cocos, sea octopus, and betel nut, and use 15 times the mass of 80% ethanol to reflux to extract. After the ethanol is recovered from the extract, ethyl acetate is used to reflux to extract. The ethyl acetate is recovered and dried under reduced pressure ...

Embodiment 3

[0055] The pharmaceutical composition for treating broiler glandular gastritis includes 90wt% Chinese medicine extract, 3wt% methionine, 2wt% lysine, and the balance is vitamin a, vitamin b2, vitamin b6, and vitamin c;

[0056] The traditional Chinese medicine extract includes 5 parts of Poria cocos, 10 parts of sea octopus, 10 parts of gardenia, 9 parts of Magnolia officinalis, 1 part of betel nut, 15 parts of bletilla striata, 23 parts of Cortex Phellodendri, 20 parts of pinellia, and 20 parts of astragalus in parts by weight. , 15 parts of angelica.

[0057] The preparation method of this pharmaceutical composition, the steps are as follows:

[0058] S1 prepares the Chinese medicine extract;

[0059] S1.1 Pulverize Poria cocos, sea octopus, and betel nut, and use 10 times the mass of 75% ethanol to reflux to extract. After recovering ethanol from the extract, use ethyl acetate to reflux to extract, recover ethyl acetate and dry under reduced pressure to obtain Chinese medi...

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PUM

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Abstract

The invention relates to a medicine compound for treating proventriculitis of broiler chicken and a preparation method thereof. The medicine compound contains traditional Chinese medicine extracts, lysine, methionine and vitamin, wherein the traditional Chinese medicine extracts contain the following materials in parts by weight: 1-5 parts of poria cocos, 10-15 parts of cuttlebone, 10-20 parts of jasmine, 8-10 parts of mangnolia officinalis, 1-5 parts of betel nut, 8-15 parts of bletilla striata, 20-25 parts of golden cypress, 15-20 parts of pinellia ternate, 10-20 parts of astragalus membranaceus and 8-15 parts of angelica sinensis. The medicine compound provided by the invention has specific traditional Chinese medicine compatibility; the advantages of the materials are complementary with one another and have a synergic effect; the medicine compound has the functions of clearing heat-fire, resolving dampness and regulating the middle warmer, diminishing inflammation and resisting bacteria and virus; the medicine compound not only can promote growth and is non-toxic and free from side effect and drug residue, but also can effectively enhance immunity, regulate glandular stomach function, restrain the secretion of gastric acid and comprehensively treat proventriculitis according to the method of protecting gastric mucosa by supplementing the nutrient substances including amino acid, vitamins, etc. The medicine compound prepared according to the invention has high therapeutic effect, the proventriculitis is free from recurrence, the efficiency can reach 85.6% and the complete healing rate can reach 67.6%.

Description

technical field [0001] The invention relates to a veterinary drug for poultry, in particular to a pharmaceutical composition for treating broiler glandular gastritis and a preparation method thereof. Background technique [0002] Chicken glandular gastritis is a common disease in poultry. The incidence rate is 7-28%, and the mortality rate is 30%-50%. The main clinical manifestations are: an infectious disease characterized by poor growth, emaciation, poor uniformity, glandular stomach enlargement, glandular gastric mucosal ulcer, and gizzard erosion. The disease has no seasonality and can occur throughout the year. It spreads quickly. Generally, chickens aged 7-10 days are the most susceptible. Chickens with chicken glandular gastritis are prone to secondary infections such as colibacillosis, mycoplasma, and Newcastle disease. , leading to an increase in mortality. The causes of the disease are divided into two aspects: infectious factors and non-infectious factors. Infe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P1/04A61P31/04A61P31/10A61K35/618A61K31/198A61K31/07A61K31/525A61K31/4415A61K31/375
CPCA61K36/898A61K31/07A61K31/198A61K31/375A61K31/4415A61K31/525A61K35/618A61K36/076A61K36/232A61K36/481A61K36/575A61K36/744A61K36/756A61K36/8888A61K36/889A61K2236/333A61K2236/39A61K2300/00
Inventor 杜雄伟李叶张来新李春斌梁军王玉山邹民发陈朝喜
Owner DALIAN NATIONALITIES UNIVERSITY
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