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Traditional Chinese medicine for treating cold-damp coagulation type allergic cutaneous vasculitis and preparation method

A cold-damp stagnation type, skin vasculitis technology, applied in skin diseases, medical formulas, cardiovascular system diseases, etc., can solve the problems of difficult dose control, unsuitable for long-term application, obvious side effects, etc., and achieve exact curative effect without adverse reactions , no toxic side effects

Inactive Publication Date: 2016-11-09
陈晓
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine hormone therapy has obvious side effects, high recurrence rate, and difficult to control dosage, so it is not suitable for long-term application

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0035] The present invention also provides the preparation method of above-mentioned Chinese medicine, and the dosage form of described Chinese medicine is tablet, and its preparation method comprises the following steps:

[0036] Step 1: Mix the components of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 70-80% that is 2-4 times the mass of the mixture, heat and reflux for 2-3 hours, extract, and filter to obtain the first extraction liquid, the dregs obtained by filtering are added with ethanol with an alcohol concentration of 1 to 2 times the mass of dregs and 70 to 80% ethanol, heated and refluxed for 1 to 2 hours, extracted, filtered to obtain a second extract, and the first extract Combine with the second extract, concentrate under reduced pressure to remove the ethanol solvent, and dry to obtain a dry paste;

[0037] The second step: place the dry paste obtained in the first step to pulverize in an ultrafine pul...

Embodiment 1

[0043] Embodiment 1: tablet

[0044] Take 160g of sharp tail wind, 110g of Jianxuefei, 220g of geranium, 180g of black milk mushroom, 340g of honeycomb grass, 200g of wild lemongrass, 140g of horseshoe grass, 130g of baby fist, 310g of horseradish grass, 530g of three-point golden grass, 240g of Tongjingcao, 120g of branched edelweiss and 170g of Edelweiss root;

[0045] Prepare as follows:

[0046] The first step: mix the components of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 80% that is 4 times the mass of the mixture, heat and reflux for 2 hours, extract, filter to obtain the first extract, and filter the obtained medicinal Then add ethanol with an alcohol concentration of 80% that is twice the mass of the dregs, heat and reflux for 1 hour, extract, filter to obtain the second extract, combine the first extract and the second extract, and concentrate under reduced pressure to remove ethanol solvent, dried to ...

Embodiment 2

[0049] Embodiment 2: Granules

[0050] Take 190g of sharp tail wind, 140g of blood fly, 200g of geranium, 160g of black milk mushroom, 320g of honeycomb grass, 230g of wild lemongrass, 120g of horseshoe grass, 110g of baby fist, 340g of horseradish grass, 510g of three golden grass, 230g Tongjingcao, 130g branched edelweiss and 150g safflower root;

[0051] Prepare as follows:

[0052] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration 3 times that of the mixture and 90% ethanol, heat to boiling and reflux for 2 hours, filter, use the reflux liquid as the solvent, and use the filter residue as the solute, Use the percolation method to percolate slowly at a rate of 2ml per minute, collect the percolation liquid, and then concentrate it under reduced pressure at a vacuum of 0.01Mpa to a paste with a relative density of 1.05 at 75°C, spray dry, and spray the dryer. The air temperature is 180°C and the outlet air temp...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating cold-damp coagulation type allergic cutaneous vasculitis and a preparation method. The traditional Chinese medicine comprises medicinal raw materials as follows: roots of Longestapex Beautyberry, roots of Spinyleaf Pricklyash, common heron's bill herb, lactarius picinus, herbs of Ceylon Leucas, herbs of Goering Lemongrass, Sibirica Walking Fern, bilobate grewia, roots and stems of Daphne koreana Nakai, Desmodium triflorum, silver aleuritopteris, Leontopodium dedekensii and roots of syzygium grijsii. The traditional Chinese medicine has the beneficial effects that the traditional Chinese medicine has definite curative effect on cold-damp coagulation type allergic cutaneous vasculitis, the curative effect is better than that of common Western medicine prednisone tablets, and toxic and side effects and adverse reactions are avoided.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating allergic skin vasculitis of cold-damp stagnation type and a preparation method thereof. Background technique [0002] Allergic cutaneous vasculitis, also known as leukocytoclastic vasculitis, is a necrotizing vasculitis that mainly involves capillaries and small blood vessels in the superficial dermis. Skin lesions are pleomorphic, such as erythema, purpura, papules, nodules, ulcers, necrosis, etc. [0003] The etiology of allergic cutaneous vasculitis is unknown, and it can be bacterial, viral infection, or allergic reaction to heterosexual proteins, drugs, and chemicals. The pathological changes were swelling and occlusion of intradermal cells in small blood vessels, surrounded by neutrophil infiltration and nuclear fragmentation. The state of an illness can show effect repeatedl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P17/00A61P9/14
CPCA61K36/899A61K9/1652A61K9/2059A61K36/06A61K36/11A61K36/185A61K36/28A61K36/48A61K36/53A61K36/61A61K36/758A61K36/83A61K36/85A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 陈晓
Owner 陈晓
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