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Method for preparing cortex phellodendri extract and application of cortex phellodendri extract composition prepared from cortex phellodendri extract in bacteriostatic agent

A technology for extracting liquid and composition, which is applied in the directions of medical preparations containing active ingredients, applications, food science, etc.

Inactive Publication Date: 2016-10-26
GUANGDONG HEJI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, so far, there is no report on the compound plant preservative obtained by compounding Phellodendron Phellodendri extract with other raw materials, so that it has a synergistic effect on antibacterial properties, thereby greatly improving its antibacterial broad-spectrum and effect.

Method used

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  • Method for preparing cortex phellodendri extract and application of cortex phellodendri extract composition prepared from cortex phellodendri extract in bacteriostatic agent
  • Method for preparing cortex phellodendri extract and application of cortex phellodendri extract composition prepared from cortex phellodendri extract in bacteriostatic agent
  • Method for preparing cortex phellodendri extract and application of cortex phellodendri extract composition prepared from cortex phellodendri extract in bacteriostatic agent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1: steam distillation method prepares Phellodendron Phellodendri extract and Phellodendron Phellodendri extract freeze-dried powder

[0038] Take 1 kg of Phellodendron cortex, dry it at 80°C, crush it to 40 mesh with a pulverizer, add distilled water according to the mass-volume solid-liquid ratio of 1:8, and carry out distillation in the distillation pot for 2 hours. The water vapor that comes out is condensed with a condenser. Collect the lower layer condensate 650ml, which is the Phellodendron Phellodendri extract prepared by the present invention. At the same time, filter the yellow concentrated liquid extracted from the bottom of the still, remove the phellodendron filter residue, add 95% ethanol so that the ethanol content in the system is 60%, let it stand for 15 minutes, then use a centrifuge at 12000rmp / min, centrifuge for 5 minutes, and take the supernatant ; Then use a rotary evaporator to dealcoholize and concentrate. Pre-freeze the concentrated ...

Embodiment 2

[0041] Embodiment 2: Phellodendron Phellodendri extract composition formula and preparation method thereof:

[0042] A Cortex Phellodendron extract composition, in parts by weight, comprises 15 parts of Cortex Phellodendri extract; 50 parts of Purslane extract; 15 parts of Magnolia magnolia extract; and 20 parts of alkanediol. The preparation method is as follows: uniformly mix the cork cortex extract, the purslane extract, the magnolia extract and the alkanediol at normal temperature to obtain the product.

[0043] Antibacterial effect test of Phellodendron Phellodendri extract composition

[0044] 1.1 Experimental test of the inhibition zone

[0045] 1.1.1 Preparation of Antibacterial Tablets

[0046] The Phellodendron Phellodendri extract composition prepared in Example 2 was configured to the concentration required for the test as required. Take the dry filter paper and put it in a 37°C incubator or dry it at room temperature for later use. (Dissolution antibacterial p...

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Abstract

The invention discloses a preparation method of Phellodendron cortex extract and the use of Phellodendron Phellodendri extract composition composed of the same as a bacteriostatic agent; the invention adopts a steam distillation method to prepare Phellodendron Phellodendri extract, which is completed in one step, and the process operation is simple. After HPLC detection, Phellodendron Phellodendri extract does not contain colored substances such as berberine hydrochloride, and does not contain organic solvents, no harmful substance residues, less irritating, colorless and transparent, light smell, in line with the concept of green and natural; will pass the steam distillation method The prepared Cortex Phellodendri extract, the Phellodendron cortex extract composition compounded with purslane extract, Magnolia oleracea extract, and alkanediol, is colorless and transparent, and has a relatively light smell. It has passed the antibacterial zone test and the antiseptic challenge test It is tested and confirmed that Phellodendron Phellodendri extract composition has good bacteriostatic effect, and it is applied to cosmetics, food, and health products as a bacteriostatic agent, with a small amount of addition, and can inhibit bacteria, mold and Antibacterial activity of fungi such as yeast.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a preparation method of Phellodendron phellodendron extract and the use of the Phellodendron phellodendron extract composition as a bacteriostatic agent. Background technique [0002] With the improvement of living standards, more and more people begin to pay attention to the safety of preservatives in cosmetics, food and health products. Traditional preservatives are mostly chemically synthesized, such as sodium benzoate, formalin, paraben, nitric acid Salt, etc., which have some risks of carcinogenicity and skin irritation in cosmetics, food, and health products. [0003] In recent years, as people favor green and natural plant sources, there are more and more researches on the development of functional skin care products using plant essences. As the safety problems of traditional preservatives are recognized by people, plant-based preservatives are favored by consumers. Because plant...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61K8/34A23L3/3472
CPCA61K8/97A23L3/3472A61K8/345A61K2800/524
Inventor 何廷刚张兵艾勇朱思阳黄垂凡张智婷
Owner GUANGDONG HEJI BIOTECH CO LTD
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