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Application of photodynamic combination of photosensitive molecules in acne treating medicine

A photosensitive molecule, photodynamic technology, applied in photodynamic therapy, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of drug-resistant skin damage, long period of physiotherapy, slow effect, etc., and achieve a small dosage. , Small side effects, strong effect

Inactive Publication Date: 2016-10-12
SUNDYNAMIC TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 2. Antibiotic method: Antibiotics are antibacterial and anti-acne, but repeated use of antibiotics can lead to drug resistance and skin damage
[0007] 4. The physiotherapy cycle of Chinese herbal medicine plant acne therapy is long and the effect is slow
For this reason, this method can only be used under the guidance of professional dermatologists

Method used

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  • Application of photodynamic combination of photosensitive molecules in acne treating medicine
  • Application of photodynamic combination of photosensitive molecules in acne treating medicine
  • Application of photodynamic combination of photosensitive molecules in acne treating medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Weigh the content of each component according to Table 2, mix 0.0001% photosensitive molecule solution with water, after fully dissolving, make up the remaining water, adjust the pH to 5, and adjust the pH to 5 at 0.1J / cm 2 Under light intensity, at a wavelength of 400nm, the bacteriostatic efficiency against Propionibacterium acnes and Staphylococcus aureus reached 99%. The control group only changed the light source and adopted natural light, and other conditions remained unchanged. The bacteriostatic efficiency of the experimental group was significantly higher than that of the control group ( See Table 3 for details).

Embodiment 2

[0039] Weigh the content of each component according to Table 2, mix 0.0001% photosensitive molecule solution with water, and after fully dissolving, make up the remaining water, adjust the pH to 7, and adjust the pH to 7. 2 Under the light intensity, under the wavelength of 600nm, the bacteriostatic efficiency against Propionibacterium acnes and Staphylococcus aureus reached 99%. The control group only changed the light source and adopted natural light, and other conditions remained unchanged. The bacteriostatic efficiency of the experimental group was significantly higher than that of the control group ( See Table 3 for details).

Embodiment 3

[0041] Weigh the content of each component according to Table 2, mix 0.0001% photosensitive molecule solution with water, and after fully dissolving, make up the remaining water, adjust the pH to 9, at 1000J / cm 2Under the light intensity, under the wavelength of 600nm, the bacteriostatic efficiency against Propionibacterium acnes and Staphylococcus aureus reached 99%. The control group only changed the light source and adopted natural light, and other conditions remained unchanged. The bacteriostatic efficiency of the experimental group was significantly higher than that of the control group ( See Table 3 for details).

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Abstract

The invention relates to application of a photodynamic combination of photosensitive molecules in acne treating medicine. The combination comprises the photosensitive molecules and a light source. The light source in the combination provides energy for activating the photosensitive molecules, photons with special energy activate photosensitizer molecules of photosensitive molecules, the photosensitive molecules transfer energy to oxygen molecules in the human body to form high-energy-state oxygen, and then high-energy oxygen molecules kill adjacent target germ propionibacterium acnes and staphylococcus aureus. The photodynamic combination of the photosensitive molecules is applied in preparation of acne treating medicine, the photosensitive molecules and the light source are effectively combined to form the photodynamic combination, and the new application of the photodynamic combination of the photosensitive molecules in the field of acne treating medicine is developed.

Description

technical field [0001] The invention provides a photodynamic combination of photosensitive molecules, and mainly relates to the application of the photodynamic combination of photosensitive molecules in acne treatment medicines. Background technique [0002] Existing acne treatment methods mainly include chemical drug therapy, Chinese herbal medicine plant acne therapy and photodynamic therapy. [0003] Chemotherapy includes the following: [0004] 1. Glucocorticoid method: Glucocorticoid itself can induce acne, and long-term use will reduce the body's immunity and cause other side effects. [0005] 2. Antibiotic method: Antibiotics are antibacterial and acne-removing, but repeated use of antibiotics can lead to drug resistance and skin damage. The drug resistance of pathogenic bacteria will make the relevant antibiotics lose their efficacy. [0006] 3. Salicylic acid (fruit acid) method: If the concentration of salicylic acid (fruit acid) is too high, the pH value is low...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K41/00A61P17/10A61P31/04
CPCA61K41/0057
Inventor 林帆刘观峰王伟杰
Owner SUNDYNAMIC TECH
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