Application of S-ademetionine in preparation of fetus protection medicines, dysmenorrhea treatment medicines and uterus health products
An adenosylmethionine and drug technology, applied in the field of medicine, can solve problems such as side effects, and achieve the effects of less side effects, reducing dysmenorrhea and premature birth, and inhibiting contractions
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[0049] Mix S-adenosylmethionine with PBS (pH7.4) to configure enough medicines for treating dysmenorrhea in three parts with different concentrations, wherein the concentration of S-adenosylmethionine solution is 0.1mmol / L, 0.3mmol / L and 1.0mmol / L respectively. mmol / L.
[0050] Repeat the above steps, mix S-adenosylmethionine with PBS (pH7.4), and configure enough three parts of different concentrations of tocolytic drugs, wherein the concentration of S-adenosylmethionine solution is 0.1mmol / L, 0.3mmol / L, respectively. L and 1.0mmol / L.
[0051] Contraction test of isolated uterine smooth muscle in ICR mice
[0052] ①Preparation of uterine smooth muscle strips from non-pregnant ICR mice
[0053] The non-pregnant ICR mice were injected with 0.5mg diethylstilbestrol (DES) 24h-48h in advance, the ICR mice were killed by cervical dislocation, the uteri were dissected, and the uterus was divided into 4-6 uterine muscle strips in the Roth's solution. The length of the muscle strip...
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