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Assay test device, kit and method of using

A technology for testing devices and diagnostic kits, which can be used in measuring devices, testing pharmaceutical preparations, biochemical equipment and methods, etc., and can solve problems such as unfavorable high absorbance

Inactive Publication Date: 2016-08-24
CREDO BIOMEDICAL PTE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Contrary to conventional printing, high absorbance is often a disadvantage

Method used

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  • Assay test device, kit and method of using
  • Assay test device, kit and method of using
  • Assay test device, kit and method of using

Examples

Experimental program
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Effect test

Embodiment 1

[0112] pH detection device and method of using the device, the device has a pH sensitive sensor, a control circuit for calculating the signal strength, and a display pixel, and the electronic components of the device are all printed by roll printing or screen printing. These are printed on a dielectric material such as flexible plastic. The production of the device avoids waste due to device breakage and is produced in high throughput. The device is useful as an LFA in which the observation of a line indicates the outcome of the reaction.

Embodiment 2

[0114] The printed electronics of Example 1 were placed on top of the LFA strips, with the pH sensitive sensor, control circuitry (to calculate signal strength) and display pixels all printed by roll-to-roll or screen printing. These electronic components are printed onto dielectrics such as flexible plastics.

[0115] Specifically, in order to measure the pH value, the printed electronic system is brought into contact with the chromatographic medium. Monitor the pH change by measuring the rate of pH change at 10 min and 30 min. Among other things, glue can be added as an intermediate layer.

Embodiment 3

[0117] Printed sensors also include printed batteries to power the circuit, or as an optional feature, coin cells. The choice of battery material should not be a fire hazard or chemical hazard in nature. Preferably, the battery includes a self-test function.

[0118] The printed sensor incorporates a display monitor (eg, OLED organic light emitting diode) to indicate the result (yes / no / fail, etc.). This printed sensor has the ability to do simple calculations. As an optional element, the sensor has a communication module (eg RFID) to upload patient information and results to a base station (such as a laptop PC, customized base station, touchpad, smart phone or a combination thereof).

[0119] Another optional element is a sensor capable of downloading patient information from a base station (eg, laptop PC, customized base station, touchpad, smartphone, or a combination thereof), such that the particular device is 'branded' with the patient's ID. These communications are opt...

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Abstract

The present invention relates to assay test devices, and methods and kits for use to monitor, sense, read and display results by using devices with printed electronics, such as batteries, reading devices, and other circuitry and / or using colorimetric means for testing by using a sensitive indicator pH dye, or both.

Description

field of invention [0001] The present invention relates to analytical test devices, kits and methods of using the test devices to sense, monitor, differentiate readings, and display the results of the device's intended test. Previous devices have been used to detect or monitor trace amounts of chemical and / or biological targets present in very low concentrations in samples including but not only biological samples, materials, organic or inorganic samples. Trace amounts of chemical and / or biological targets can include biological / chemical products, fragments or whole targets, such as nucleic acid sequences, cells, viruses, pathogens, chemicals, which are useful in fields such as pharmacogenomics, pathogen detection and monitoring, genetic predisposition determination, Genetic classification for clinical trials, diagnostics, prognostics, diagnostics and monitoring of infectious diseases, biocontainment, forensic analysis, paternity testing, animal and plant breeding, food testin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/15G01N30/02G01N21/78G01N33/53G01N33/573
CPCG01N33/54388C12Q1/6816C12Q1/6844G01N21/80G01N33/581G01N33/582G02B5/223H05K3/1216C12Q2531/119C12Q1/703G01N27/4145G01N27/4167G01N33/5438G01N33/84C12Q2600/158G01N2021/752C12Q1/686G01N21/78
Inventor 欧昌沛萨格尔·考沙尔阿卜杜勒·鲁布·阿卜杜勒·拉曼温斯顿·王·二世高章琦马奎斯·卡蒂亚
Owner CREDO BIOMEDICAL PTE
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