Feed additive coating material and preparation method thereof

Abstract

The invention discloses a coating material for coating a feed additive. The coating material is a random quadripolymer which is synthesized by taking styrene, 2-vinplpyridine, 2-tert-butylaminoethyl methacrylate and 2-methacryloyloxyethyl phosphorycholine as raw materials according to the monomer mole feed ratio of (2.5-4):(2.5-6):(0.5-3):(0.5-3). The quadripolymer is synthesized by designing a molecular structure. Through the specific proportion and synergistic effect among the four monomers in the polymer, the coating material has the advantages of being sensitive to pH, good in coating stability, few in monomer residue, capable of not damaging genetic materials, good in biocompatibility and the like.

Description

technical field [0001] The invention relates to a coating material for coating feed additives and a preparation method thereof. Background technique [0002] When ruminants generally eat, most of the food, especially roughage, is swallowed into the rumen without being fully chewed. After soaking and softening in the rumen for a period of time, the food returns to the mouth through regurgitation, chews again, mixes with saliva again, and then Swallowing into the abomasum for final digestion. Generally speaking, the rumen contains a large number of microorganisms, and the food stored in the rumen has higher nutritional value after being fermented. However, for fed nutrients or drugs, this special phenomenon of rumen digestion often leads to the loss of nutrients or drugs. Lost in the rumen. Some amino acids such as methionine can be dissolved in water when the pH is greater than or equal to 5.5, while the pH in the rumen environment is about 5.5 and ruminants will keep food ...

AI Technical Summary

Problems solved by technology

However, the price of pyridine derivative monomers is relatively high, and they are generally unstable and easily oxidized, which makes their storage difficult and increases the cost of use.

[0006] Although some feed coating copolymers that can be used as physical protection methods have been synthesized at present, which have a narrow pH sensitive range and have certain protection effects on feed in the rumen, they have not yet overcome their poor biocompatibility, poor coating stability, The residual monomers of synthetic materials are difficult to meet the standards for medical use; in particular, monomers such as acrylamide will combine with guanine on DNA to form adducts when they enter the animal body, resulting in genetic material damage such as gene mutations

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