Eureka AIR delivers breakthrough ideas for toughest innovation challenges, trusted by R&D personnel around the world.

Stable montelukast oral rapidly disintegrating film as well as preparation method and application thereof

An oral instant film and film-forming material technology, applied in the field of medicine, can solve the problems of low mechanical strength, low hardness of orally disintegrating tablets, difficulty in packaging and transportation of finished products, and achieve the effect of outstanding stability and high stability

Inactive Publication Date: 2016-08-24
天津康鸿医药科技发展有限公司
View PDF3 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Orally disintegrating tablets usually have low hardness and low mechanical strength, which brings difficulties to the packaging and transportation of finished products

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Stable montelukast oral rapidly disintegrating film as well as preparation method and application thereof
  • Stable montelukast oral rapidly disintegrating film as well as preparation method and application thereof
  • Stable montelukast oral rapidly disintegrating film as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038]

Embodiment 2

[0040]

Embodiment 3

[0042]

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Wavelengthaaaaaaaaaa
Login to View More

Abstract

The invention belongs to the technical field of medicine, and in particular relates to a stable oral instant montelukast film and its preparation method and application, wherein the film-forming material is a mixture of sodium hydroxypropyl methylcellulose and polyvinyl alcohol in a certain proportion . The product has high stability and is suitable for large-scale industrial production.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an oral instant film with montelukast as an active ingredient, a preparation method and application thereof. Background technique [0002] Montelukast sodium is an oral leukotriene receptor antagonist developed by Merck & Co. (known as Merck in the United States and Canada) that specifically inhibits the cysteinyl leukotriene (CysLT1) receptor in the airways , so as to improve airway inflammation and effectively control asthma symptoms. Montelukast sodium is a non-hormonal anti-inflammatory drug, suitable for the prevention and long-term treatment of asthma and the treatment of allergic rhinitis in adults and children over 1 year old, with three different specifications. Leukotriene modulators are the only long-term control drugs that can be used alone in addition to inhaled hormones. They can be used as an alternative treatment drug for mild asthma and a combined t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K9/70A61K31/404A61P11/06A61P11/02
Inventor 吴疆孙歆慧王成港邹美香刘欢刘钫王安宋爱丽
Owner 天津康鸿医药科技发展有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products