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Biomimetic design osteoid porous bone product and preparation method thereof

A porous bone and bone-like technology, applied in the field of biomedical materials, can solve the problems of high production cost, long processing cycle and high equipment requirements, and achieve the effects of fast processing, small footprint and shortened cycle.

Active Publication Date: 2017-12-15
成都百年贝雅医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The existing processing of titanium and titanium alloy implants requires precise cutting, which consumes a lot of materials, requires high equipment, and has a long processing cycle, resulting in high production costs.

Method used

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  • Biomimetic design osteoid porous bone product and preparation method thereof
  • Biomimetic design osteoid porous bone product and preparation method thereof
  • Biomimetic design osteoid porous bone product and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] In the modeling software, place nine hollow spherical shells, such as figure 1 As shown, the position of the center of the sphere is strictly in accordance with the position of the BCC atoms in crystallography. The outer radius of the spherical shell is 0.75mm, the inner radius is 0.55mm, and there will be holes with a diameter of 0.3mm on the spherical shell. The pores of this model The ratio is 59.83%, the pore diameter is 350±20 μm, and the interpenetrating micropore diameter is 90±10 μm.

[0030] Using pure titanium spherical powder as raw material, using the above-mentioned unit body as the pore structure unit, array in three-dimensional space and then perform excision / Boolean operation to obtain bone-like porous titanium nail rod products, such as figure 2 shown. Export the design as an STL format file and input it into a 3D printer for printing.

Embodiment 2

[0032] Modeling is carried out in the modeling method of Example 1, wherein the outer radius of the spherical shell is 0.7mm, the inner radius is 0.5mm, the diameter of the spherical shell hole is 400mm, and other parameters remain unchanged. Using pure titanium spherical powder as raw material, convert the 3D model of the designed product into an STL format file, input it into a 3D printer for printing and molding, and obtain a product with a porosity of 74.4%, a pore diameter of 400±20 μm, and an interpenetrating micropore diameter of 200± 10 μm.

Embodiment 3

[0034] Modeling is carried out in the modeling method of Example 1, wherein the outer radius of the spherical shell is 0.7mm, the inner radius is 0.35mm, the diameter of the spherical shell hole is 300mm, and other parameters remain unchanged. Using pure titanium spherical powder as raw material, convert the 3D model of the designed product into an STL format file, and input it into a 3D printer for printing and molding, such as image 3 As shown, the porosity of the obtained product is 85.2%, the pore diameter is 300±20 μm, and the interpenetrating micropore diameter is 200±10 μm.

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Abstract

The invention relates to a bionics design bone-line porous bone product and a preparation method and a purpose thereof, and belongs to the field of biomedical materials. The bionics design bone-line porous bone product is of a body-centered three-dimensional lattice micropore space structure, the atom positions of a unit body of the micropore space structure are filled by geometries, each geometry is a sphere casing or a sphere body, and is crossed with the surrounding sphere casings or the sphere bodies, and a through circular hole is formed in each crossing part. The bionics design bone-line porous bone product has the advantages that by utilizing a three-dimensional printing quick forming manufacturing technique, the excessive cutting waste is avoided, the utilization rate of material is high, and the processing is rapid; the bone-line porous bone nails, bars and plates prepared by the bionics design bone-line porous bone product are used for the human body hard tissue defect repair, bone tissue engineering stents, and bearing part bone tissue wound repair and reconstruction, the good structure integrity and shape customizing capability are realized, various shapes can be processed according to the patient bone tissue defect repair requirements, and the personalized medical requirements of the patient are met.

Description

technical field [0001] The invention relates to a bionic design bone-like porous bone product, a preparation method and application thereof, and belongs to the field of biomedical materials. Background technique [0002] Due to their excellent corrosion resistance, biocompatibility, low density and high specific strength, titanium and titanium alloys have been widely used in medical surgery, especially in the field of bone repair. Biomedical implants are special functional materials closely related to human life and health. Compared with other metal materials, titanium and titanium alloys have huge inherent advantages. At room temperature, the density of titanium and titanium alloys is 4.5g / cm 3 , Only 56% of stainless steel. Implantation in the body can greatly reduce the load of the implant; at the same time, the elastic modulus of titanium and titanium alloys is low, pure titanium is 108.5GPa, which is only 53% of stainless steel, and the implantation in the body is cl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/28B33Y10/00B33Y70/00A61L27/06A61L27/32A61L27/56
CPCA61F2/28A61F2230/0071A61L27/06A61L27/32A61L27/56B33Y10/00B33Y70/00
Inventor 樊渝江周长春裴玄朱向东王亚宁殷国富张兴栋
Owner 成都百年贝雅医疗科技有限公司
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