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A medicinal composition for treating chronic pharyngitis and its preparation method and application

A technology of chronic pharyngitis and composition, which is applied in the field of pharmaceutical composition for treating chronic pharyngitis and its preparation, which can solve problems such as inaccurate curative effect, achieve obvious economic and social benefits, less medicinal taste, and good application value

Active Publication Date: 2019-06-21
YANGTZE RIVER PHARM GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The curative effect of western medicine is not exact. Although the use of burning method can improve the foreign body sensation in the pharynx, it often leads to dry throat and aggravated sore throat due to the destruction of glandular secretion of mucous membrane and scar contracture. Traditional Chinese medicine treats chronic pharyngitis Compared with western medicine, it has its unique curative effect

Method used

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  • A medicinal composition for treating chronic pharyngitis and its preparation method and application
  • A medicinal composition for treating chronic pharyngitis and its preparation method and application
  • A medicinal composition for treating chronic pharyngitis and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] 10 parts of Astragalus, 20 parts of Ligustrum lucidum, 6 parts of Atractylodes macrocephala (stir-fried), 18 parts of Poria cocos, 6 parts of turmeric, 8 parts of lacquer, and 2 parts of wood butterfly. Add water with a volume-to-weight ratio of 6-10 times, decoct 3 times, each time for 1-2 hours, and combine the decoction; filter the decoction, and concentrate the filtrate to a relative density of 1.10-1.20; alcohol precipitation, the alcohol content is 50-70%, stand still, and the standing time is 12-48h; the alcohol precipitation solution is concentrated to a relative density of 1.20-1.25 at 50°C-70°C, and dried to obtain a dry extract; the above dry extract is crushed and sieved , to obtain extract powder; add dextrin or lactose or starch or magnesium stearate and stevia to the above extract powder, mix, granulate, and compress to form tablets.

Embodiment 2

[0038] 15 parts of astragalus, 15 parts of Ligustrum lucidum, 12 parts of Atractylodes macrocephala (stir-fried), 12 parts of poria cocos, 12 parts of turmeric, 6 parts of lacquer, and 3 parts of wood butterfly. Add water with a volume-to-weight ratio of 6-10 times, decoct 3 times, each time for 1-2 hours, and combine the decoction; filter the decoction, and concentrate the filtrate to a relative density of 1.10-1.20; alcohol precipitation, the alcohol content is 50-70%, stand still, and the standing time is 12-48h; the alcohol precipitation solution is concentrated to a relative density of 1.20-1.25 at 50°C-70°C, and dried to obtain a dry extract; the above dry extract is crushed and sieved , to obtain extract powder; add dextrin or lactose or starch or microcrystalline cellulose and stevia to the above extract powder, mix well, and granulate to make granules.

Embodiment 3

[0040] 20 parts of Astragalus, 10 parts of Ligustrum lucidum, 18 parts of Atractylodes macrocephala (fried), 6 parts of Poria cocos, 18 parts of turmeric, 4 parts of lacquer, and 6 parts of wood butterfly. Add water with a volume-to-weight ratio of 6-10 times, decoct 1-3 times, 1-2 hours each time, combine the decoction liquid; filter the decoction liquid, and concentrate the filtrate to a relative density of 1.10-1.20; alcohol precipitation, containing alcohol The amount is 50-70%, and the standing time is 12-48h; the alcohol precipitation solution is concentrated to a relative density of 1.20-1.25 at 50°C-70°C, and dried to obtain a dry extract; crush the above dry extract, Sieve to obtain extract powder; add dextrin or lactose or starch and stevia to the above extract powder, mix well, granulate, divide into capsules, and then make capsules.

[0041] Pharmacodynamic test

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Abstract

The invention discloses a pharmaceutical composition for treating chronic pharyngitis and a preparation method and application thereof. The composition is prepared from active ingredients mainly comprising, by weight, 10-20 parts of radix astragali, 10-20 parts of prepared glossy privet fruits, 6-18 parts of rhizoma atractylodis macrocephalae, 6-18 parts of poria cocos, 6-18 parts of radix curcumae, 4-8 parts of sun euphorbia herb and 2-4 parts of semen oroxyli. The pharmaceutical composition has the functions of nourishing yin and tonifying qi and regenerating body fluid and moistening dryness, and is used for treating chronic pharyngitis. The pharmaceutical composition is convenient to take, stable in function, define in curative effect, stable in dosage form, controllable in quality, free of toxic and side effect and capable of meeting the needs of patients.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a medicinal composition for treating chronic pharyngitis made from traditional Chinese medicines, a preparation method and application thereof. Background technique [0002] Chronic pharyngitis is a diffuse inflammation of the pharyngeal mucosa, submucosal and lymphoid tissues, often a part of chronic inflammation of the upper respiratory tract, and is a common and frequently-occurring disease in clinical practice. The disease has a long course of disease and is lingering and difficult to heal. It has always been a difficult problem in the Department of Otorhinolaryngology, and it also brings great pain to patients. With the continuous development of industry, air and water pollution are serious, coupled with bad living habits and abuse of antibiotics, etc., causing respiratory diseases to increase day by day, especially chronic pharyngitis, whic...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P11/04
CPCA61K36/076A61K36/185A61K36/284A61K36/47A61K36/481A61K36/638A61K36/9066A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 谭琴何倩灵赵静姚仲青李娜陈钟李鹏
Owner YANGTZE RIVER PHARM GRP CO LTD
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