Traditional Chinese medicinal composition for treating membranous nephropathy and method for preparing traditional Chinese medicinal composition for treating membranous nephropathy

Abstract

The invention relates to a traditional Chinese medicinal composition for treating membranous nephropathy and a method for preparing the traditional Chinese medicinal composition for treating the membranous nephropathy. The traditional Chinese medicinal composition is prepared from the following raw materials in proportions by weight: 60 to 120 parts of radix astragali seu hedysari, 15 to 30 parts of radix rehmanniae recens, 15 to 30 parts of radix rehmanniae preparata, 15 to 30 parts of gorgon fruit, 15 to 30 parts of Chinese pyrola herb, 30 to 90 parts of rhizoma smilacis glabrae, 30 to 90 parts of herba hedyotidis diffusae, 15 to 30 parts of radix salviae miltiorrhizae, 0.5 to 3 parts of hirudo recens, 6 to 12 parts of herba schizonepetae and 6 to 12 parts of radix saposhnikoviae. The raw materials are extracted according to a certain technical method, and then are made, together with pharmaceutically acceptable accessories, into a traditional Chinese medicinal oral preparation. The traditional Chinese medicinal composition which is provided by the invention has the effects of tonifying spleen and kidney, supplementing qi, nourishing yin, removing dampness through diuresis and promoting blood circulation, and is used for treating various kinds of acute and chronic nephritis, and proteinuria and edema which are caused by a nephrotic syndrome.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating membranous nephropathy and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. Background technique [0002] Membranous nephropathy (IMN) is a group of diseases characterized by deposition of immune complexes under the glomerular basement membrane epithelial cells and diffuse thickening of the basement membrane. Hairy. Among them, idiopathic membranous nephropathy (IMN) is one of the common pathological types of primary nephrotic syndrome, accounting for about one-third of adult nephrotic syndrome. The natural course of the disease varies widely, with different outcomes such as spontaneous remission, persistent proteinuria, and deterioration of renal function. Currently, there is no effective treatment, and about 30% of patients progress to end-stage renal failure within 5-10 years. [0003] This disease belongs to the categor...

AI Technical Summary

Problems solved by technology

However, long-term use found that there are many shortcomings in this prescription: Rehmannia glutinosa is cold and cool, and long-term use can easily damage the spleen and stomach, resulting in poor appetite, abdominal distension, and thick and greasy tongue coating.

In clinical application, it is found that the therapeutic effect of the drug is not ideal enough. Therefore, it is of great significance to develop a more effective traditional Chinese medicine preparation.

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