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Medicine with function of treating cerebrovascular diseases, method for preparing medicine and application thereof

A technology for cerebrovascular diseases and drugs, applied in the field of drugs for the treatment of cerebrovascular diseases and its preparation, can solve the problems of unfavorable patients swallowing, large dosage, slow absorption, etc., to reduce brain index and brain water content, improve brain Function, the effect of dilating cerebral blood vessels

Inactive Publication Date: 2016-08-10
王政乾
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But it is not difficult to see that the current oral preparations for the treatment of cerebrovascular diseases generally have the disadvantages of large dosage, which is not conducive to swallowing by patients, slow absorption, and slow onset of action

Method used

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  • Medicine with function of treating cerebrovascular diseases, method for preparing medicine and application thereof
  • Medicine with function of treating cerebrovascular diseases, method for preparing medicine and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] 1. Prescription:

[0021] Leech 200g, ginseng 180g, dodder 60g;

[0022] 2. Preparation method:

[0023] Ginseng was crushed to make medicinal powder; leech and dodder were refluxed and extracted with ethyl acetate: ethanol = 1: 1 for 1 hour to obtain an extract, which was passed through an ODS-C18 column, first using 30% ethanol as the mobile phase, and then using 90 % ethanol as the mobile phase to obtain the eluate, concentrate and dry the eluate, and continue to separate the intermediate product obtained by preparative liquid chromatography; decoct chrysanthemum and kudzu root in water, decoct twice, each time for 30 minutes, and combine the medicines liquid, filtered, concentrated, added ethanol, removed the precipitate, and recovered the ethanol to obtain the concentrated liquid; the concentrated liquid, the intermediate product was added to the medicinal powder, an appropriate amount of excipients was added, mixed evenly, and packaged to obtain final product;

...

Embodiment 2

[0026] 1. Prescription:

[0027] Leech 180g, ginseng 160g, dodder 80g;

[0028] 2. Process:

[0029] Ginseng was crushed to make medicinal powder; leech and dodder were refluxed and extracted with ethyl acetate: ethanol = 1: 1 for 1 hour to obtain an extract, which was passed through an ODS-C18 column, first using 30% ethanol as the mobile phase, and then using 90 % ethanol as the mobile phase to obtain the eluate, concentrate and dry the eluate, and continue to separate the intermediate product obtained by preparative liquid chromatography; decoct chrysanthemum and kudzu root in water, decoct twice, each time for 30 minutes, and combine the medicines liquid, filtered, concentrated, added ethanol, removed the precipitate, and recovered the ethanol to obtain the concentrated liquid; the concentrated liquid, the intermediate product was added to the medicinal powder, an appropriate amount of excipients was added, mixed evenly, and packaged to obtain final product;

[0030] The...

Embodiment 3

[0032] 1. Prescription:

[0033] Leech 130g, ginseng 130g, dodder 50g;

[0034] 2. Preparation method:

[0035] Ginseng was crushed to make medicinal powder; leech and dodder were refluxed and extracted with ethyl acetate: ethanol = 1: 1 for 1 hour to obtain an extract, which was passed through an ODS-C18 column, first using 30% ethanol as the mobile phase, and then using 90 % ethanol as the mobile phase to obtain the eluate, concentrate and dry the eluate, and continue to separate the intermediate product obtained by preparative liquid chromatography; decoct chrysanthemum and kudzu root in water, decoct twice, each time for 30 minutes, and combine the medicines liquid, filtered, concentrated, added ethanol, removed the precipitate, and recovered the ethanol to obtain the concentrated liquid; the concentrated liquid, the intermediate product was added to the medicinal powder, an appropriate amount of excipients was added, mixed evenly, and packaged to obtain final product;

...

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Abstract

The invention relates to a medicine with a function of treating cerebrovascular diseases. The medicine comprises, by weight, 10-25 parts of hirudo, 10-25 parts of radix ginseng and 1-10 parts of semen cuscutae. The invention further discloses a method for preparing the medicine and application thereof. The medicine, the method and the application have the advantage that qi deficiency and blood stasis type cerebrovascular diseases, cerebral stroke, hypertension, hemiplegia, voice loss and aphasia, mouth and tongue deviation and hemianesthesia syndromes mainly can be treated by the medicine in a formula.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a medicine for treating cerebrovascular diseases, a preparation method and application thereof. Background technique [0002] Cerebrovascular disease (cerebrovascular disease) is a clinical common and frequently-occurring disease with high mortality and disability, which brings a heavy burden to families and society. According to relevant statistics, with the change of people's lifestyle, my country has become a high-incidence area for this type of disease. Western medicine mostly uses treatment methods such as thrombolytic therapy and anticoagulant therapy. These methods have certain curative effects, but there are weak curative effects, Shortcomings such as slow effect and long treatment period can also cause side effects such as subcutaneous hemorrhage, gastrointestinal hemorrhage, and cerebral hemorrhage. [0003] In recent years, my country's medical community has...

Claims

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Application Information

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IPC IPC(8): A61K36/39A61P9/00A61P9/10A61P9/12A61P25/00A61K35/62
CPCA61K35/62A61K36/258A61K36/39A61K2236/333A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 王政乾
Owner 王政乾
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