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Application of ulinastatin in preparation of medicine for treating chronic prostatitis

A technology of chronic prostatitis and ulinastatin, which is applied in the field of medicine, can solve problems such as ulinastatin discovered in research, achieve significant therapeutic effects, improve disease conditions, and facilitate rehabilitation

Active Publication Date: 2019-09-10
GUANGDONG TECHPOOL BIO-PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But, so far, there is no research to find that ulinastatin is used for preparing the purposes in the medicine for the treatment of chronic prostatitis

Method used

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  • Application of ulinastatin in preparation of medicine for treating chronic prostatitis
  • Application of ulinastatin in preparation of medicine for treating chronic prostatitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1, preparation ulinastatin freeze-dried powder injection

[0021] Take 100 million units of ulinastatin aqueous solution after filtration sterilization, add 20 grams of mannitol to dissolve, adjust the pH to neutral, add water for injection to 2000 ml, add sodium chloride to adjust isotonicity, filter aseptically, and pack in In 1000 vials, freeze-dry under aseptic conditions to get final product.

Embodiment 2

[0022] Embodiment 2, preparation ulinastatin injection

[0023] Take 100 million units of ulinastatin aqueous solution after filtration sterilization, add 20 grams of mannitol to dissolve, adjust the pH to neutral, add water for injection to 2000 ml, add sodium chloride to adjust isotonicity, filter aseptically, and pack 1000 Get it in a vial.

Embodiment 3

[0024] Embodiment 3, preparation ulinastatin injection

[0025] Take 100 million units of ulinastatin aqueous solution after filtration sterilization, add 20 grams of glucose to dissolve, adjust the pH to neutral, add water for injection to 2000 ml, add sodium chloride to adjust isotonicity, filter aseptically, and pack 1000 pieces Get it in a vial.

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Abstract

The invention belongs to the field of medicines, and particularly relates to an application of ulinastatin in preparing medicines for treating chronic prostatitis.According to the application of ulinastatin in preparing the medicines for treating chronic prostatitis, experiments show that ulinastatin injection can remarkably reduce the prostate wet weight, size and prostate index of rats suffering chronic prostatitis, the effect of a high-dose group is best, and it shows that ulinastatin has a remarkable treatment effect on chronic prostatitis.Prostate tissue pathological examinations show that ulinastatin can remarkably improve the pathological changes of tissues of chronic prostatitis and is more beneficial for recovery of patients suffering chronic prostatitis.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the use of ulinastatin in the preparation of medicines for treating chronic prostatitis. Background technique [0002] Prostatitis is a kind of genitourinary system disease that young and middle-aged men often suffer from. It is clinically divided into two types: acute prostatitis and chronic prostatitis, among which chronic prostatitis is the most common. Chronic prostatitis mostly occurs in men aged 18-45, and is a clinical syndrome mainly manifested by urination irritation and pain in the genital area of ​​the bladder. Its pathogenesis is complex and diverse, for example: prostate congestion, urine stimulation, pathogenic microorganism infection, decreased immunity, allergies, and long-term anxiety, depression, and fear can all cause chronic prostatitis. [0003] Patients with chronic prostatitis often have adverse symptoms such as lumbosacral, perineal, and testicular pai...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/57A61P13/08
Inventor 宋建东叶晓春孙明晖侯维静赵菁
Owner GUANGDONG TECHPOOL BIO-PHARMA CO LTD
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