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Use of forsythiagenin in the preparation of medicines for treating hepatitis B

A technology of viral hepatitis and forsythia aglycone, which is applied in the field of medicine, can solve the problems of high toxicity and side effects of drugs, and achieve the effects of definite curative effect, inhibition of drug withdrawal rebound, and no drug resistance

Active Publication Date: 2021-08-31
SHANDONG NEWTIME PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In order to overcome the shortcomings of the existing hepatitis B treatment drugs, which have large toxic and side effects and are prone to tolerance during the treatment process, the present invention provides an effective therapeutic drug for treating hepatitis B

Method used

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  • Use of forsythiagenin in the preparation of medicines for treating hepatitis B
  • Use of forsythiagenin in the preparation of medicines for treating hepatitis B
  • Use of forsythiagenin in the preparation of medicines for treating hepatitis B

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1 Forsythiagenin Injection

[0021]

[0022] Preparation process: mix the prescribed amount of propylene glycol and ethanol evenly, add forsythiagenin, stir to dissolve, add the prescribed amount of 0.9% sodium chloride solution, stir evenly, add 0.5% needle, stir with activated carbon, decarbonize, and then pack it. .

Embodiment 2

[0023] Example 2 Forsythiagenin Injection

[0024]

[0025] Preparation process: mix the prescribed amount of PEG-400 with ethanol, add forsythiaside, stir to dissolve, add 0.9% sodium chloride solution to 10000ml, stir evenly, add 0.5% needle, stir with activated carbon, decarbonize, and then pack it. .

Embodiment 3

[0026] Example 3 Forsythiagenin Injection

[0027]

[0028] Preparation process: Mix the prescribed amount of ethanol and Tween-80 evenly, add forsythiagenin, stir to dissolve, add water for injection to 10000ml, stir evenly, add 0.5% activated carbon for needles, stir for decarbonization, and then divide and pack.

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PUM

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Abstract

The invention belongs to the field of medicine and relates to the use of forsythiaside in the preparation of medicines for treating hepatitis B virus. In order to overcome the disadvantages of existing hepatitis B therapeutic drugs, such as large toxic and side effects and easy tolerability in the course of treatment, the invention provides an effective therapeutic drug for treating viral hepatitis B. The therapeutic drug uses forsythiagenin as the active ingredient. When it is used in the treatment of patients with hepatitis B virus, it not only has a direct anti-hepatitis B virus effect, but also can inhibit the secretion of HBsAg and HbeAg by the hepatitis B virus, and can repair Liver injury caused by virus infection has definite curative effect, less toxic and side effects, good safety and tolerance, and has a very wide prospect of medical application.

Description

technical field [0001] The invention relates to a new medical application of forsythiagenin, in particular to the application of forsythinin in the preparation of medicines for treating viral hepatitis B, and belongs to the field of medicine. Background technique [0002] Hepatitis B is a disease caused by hepatitis B virus (HBV), which is mainly characterized by liver inflammatory lesions and can cause multiple organ damage. The disease is widely prevalent in all countries in the world, mainly affecting children and young adults, and a small number of patients can be transformed into liver cirrhosis or liver cancer. Therefore, it has become a worldwide disease that seriously threatens human health, and it is also the most widespread and most harmful disease in my country. Hepatitis B has no certain epidemic period, and it can occur throughout the year, but most of them are sporadic. In recent years, the incidence of HBV has been increasing significantly. [0003] The goa...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/34A61P1/16A61P31/20
Inventor 张贵民冯芹姜明敏商庆节吕金钢刘艳松
Owner SHANDONG NEWTIME PHARMA
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