CPG (Central Pattern Generator)-based cardiopulmonary rhythm synchronous control experimental platform

Abstract

The invention provides a CPG (Central Pattern Generator)-based cardiopulmonary rhythm synchronous control experimental platform. The CPG-based cardiopulmonary rhythm synchronous control experimental platform comprises two parts, namely an FPGA (Field Programmable Gate Array) development board and an upper computer, wherein the two parts are mutually connected through a USB (Universal Serial Bus) interface; the FPGA development board is used for realizing a cardiac muscle cell network model, a CPG model and an FFT (Fast Fourier Transform) algorithm; the upper computer is used for designing an upper computer software interface by adopting LabVIEW and is in communication with the FPGA development board. The CPG-based cardiopulmonary rhythm synchronous control experimental platform provided by the invention has the effects that through an FPGA neural network experimental platform based on high-speed computation which is used for carrying out non-animal testing on biological neural networks, regulation and control of a CPG on cardiopulmonary rhythm synchronization are realized, and the time-scale consistency with real biological neurons can be ensured; according to the CPG-based cardiopulmonary rhythm synchronous control experimental platform, a visual research platform which is more approximate to a real neural network is provided for researching a mechanism and control of the cardiopulmonary rhythm synchronization, and the CPG-based cardiopulmonary rhythm synchronous control experimental platform has the important practical value in researching and treating multiple cardiopulmonary diseases comprising a cardiovascular disease and the like.

Description

technical field [0001] The invention relates to biomedical engineering technology, in particular to a CPG-based cardiopulmonary rhythm synchronization control platform. Background technique [0002] In the past 20 years, the coupling phenomenon between breathing and heart rate has received more and more attention in the medical field. Findings in cardiovascular physiology suggest that temporal variability in respiration and heart rate are often correlated. The main manifestation is that when inhaling, the release of catecholamines increases, the sinus P-P cycle shortens, and the heart rate increases; when exhalation, acetylcholine is produced, causing excessive polarization of the sinoatrial node, prolonging the sinus P-P cycle, and slowing down the heart rate. This synchronous sinus rhythm and breathing rhythm phenomenon is called respiratory arrhythmia (Respiratory sinusarrhythmia, RSA). RSA is a physiological phenomenon resulting from the interaction between the respira...

AI Technical Summary

Problems solved by technology

[0006] The existing technology is still in the basic stage, and still has the following shortcomings: there is no FPGA experimental platform for cardiopulmonary rhythm modulation based on CPG; the structure of the CPG model and cardiomyocyte model implemented by hardware is relatively simple, and the practical application value is low; the cardiopulmonary rhythm regulation method adapts to poor performance; human-machine interface is not yet perfect

Therefore, it is difficult to operate and analyze the FPGA hardware CPG network and myocardial network model

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