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Medicine composition for treating blood stasis heating type postpartum fever and preparation method thereof

A postpartum fever and composition technology, which is applied in the direction of drug combination, antipyretics, and pharmaceutical formulas. Less side effects and simple production process

Inactive Publication Date: 2016-05-11
济南思拓新源医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When chemically synthesized drugs act on the body, they will change the pH and osmotic pressure in the body, interfere with non-lesional parts and links, and easily cause damage to the protoplasm of cells, causing toxic and side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0066] The dosage form of the pharmaceutical composition is oral liquid, and its preparation method comprises the following steps:

[0067] The first step is to mix the saffron, Sanleng, Jiubiying and Nvwei, add 3 to 5 times the amount of ethanol with an alcohol concentration of 55% to 65% for reflux extraction 2 to 4 times, each After 2 hours to 3 hours, filter, combine the filtrates, recover ethanol, concentrate to a paste with a relative density of 1.30 to 1.32 at 70°C, and set aside;

[0068]The second step is to mix the remaining raw medicinal materials in proportion, add 3 to 5 times the amount of water relative to the mixture, boil for 2 to 4 hours, filter, and concentrate to a paste with a relative density of 1.27 to 1.29 at 70°C;

[0069] The third step is to mix the paste obtained in the first step and the second step, and dry under reduced pressure and vacuum at 55°C to 65°C to obtain a dry paste;

[0070] In the fourth step, ethanol is added to the dry cream powde...

Embodiment 1

[0081] Embodiment 1 oral liquid

[0082] The preparation process of the oral liquid of the present invention is as follows: take 140g of the root of Smilax chinensis, 320g of Baiqian, 240g of Saffron safflower, 320g of Sanleng, 250g of Jiubingying, 40g of female wilt, 320g of Scutellaria chinensis, 220g of Spoonleaf grass, and Guya 180g, orchid seven 320g, Gentiana chinensis 230g, Goucatecha 260g, leaf flower 30g, comfrey velvet 40g, sand mustard 210g, peach leaf Polygonum 150g, hemp seed 320g, citrus aurantium 140g, halberd leaves 270g, Codonopsis pilosula 300g, Niu Mateng 250g, Fangji 200g, Jasmine laurel 320g, Coptis 240g, Bai Wei 400g, Dioscorea 130g and Hanberry root 300g.

[0083] Its preparation method comprises the following steps:

[0084] The first step is to mix the safflower, Sanleng, Jiubiying and Nvwei, add 60% ethanol with an alcohol concentration 4 times the amount of the mixture, and reflux extraction for 3 times, each time for 2 hours, filter, and combine th...

Embodiment 2

[0090] Embodiment 2 Granules

[0091] The preparation process of the granules of the present invention is as follows: get 160g of Smilax root, 320g of Baiqian, 220g of Saffron safflower, 300g of Sanleng, 210g of Jiubingying, 30g of female wilt, 320g of Scutellaria chinensis, 240g of Spoonleaf grass, and Guya 300g, orchid seven 330g, Gentiana chinensis 280g, Gou catechu 200g, leaf flower 20g, comfrey velvet 30g, sand mustard 210g, peach leaf Polygonum 160g, hemp seed 330g, aurantium 180g, halberd leaves 220g, Codonopsis pilosula 300g, Niu Ma Teng 210g, Fangji 170g, Jasmine laurel 330g, Coptis 200g, Bai Wei 400g, Dioscorea 140g, Hanberry root 240g, Fern 150g, Melaleuca 300g and paired leaves 120g.

[0092] Preparation methods include:

[0093] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 95% that is 7 times that of the mixture, heat to boiling and reflux for 4 hours, filter, and use percolation method at a r...

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Abstract

The invention provides a medicine composition for treating blood stasis heating type postpartum fever and a preparation method thereof. The medicine composition is prepared from melastoma dodecandrum lour roots, cynanchum glaucescens, zephyranthes carinata herbs, trigone, ilex rotunda thunb, China pulsatilla, thorny elaeagnus fruits, latouchea fokiensis, rice sprout, caulophyllum robustum, large-leaved gentian, berchemia sinica, ainsliaea pertyoides franch, shellac, cornutcd pugionium, polygonum persicaria, fructus cannabis, immature bitter oranges, lepisorus waltonii hing) Ching, codonopsis pilosula, evergreen mucuna roots and leaves, radix stephaniae tetrandrae, jasminum laurifolium, coptis chinensis, cynanchum atratum, dioscorea cirrhosa and rubus buergeri roots. When the medicine composition is used for treating blood stasis heating type postpartum fever, promoting blood circulation to remove blood stasis and treating deficiency of vital energy serve as principles, the effects of replenishing blood, clearing heat and deficiency, helping digestion and invigorating stomach are also achieved, and the medicine composition mainly treats blood stasis heating type postpartum fever and has the advantages of being simple and convenient in preparation process, small in toxic or side effect, convenient to take, good in curative effect and the like.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a pharmaceutical composition for treating postpartum fever of blood stasis and fever type and a preparation method thereof. Background technique [0002] Western medicine's understanding of this disease is: puerperal infection refers to reproductive tract infection after childbirth and puerperium, also known as "puerperal fever", the incidence rate is about 17.2%. Since the vast majority of puerperal fever is caused by puerperal infection, postpartum fever of blood stasis fever type can be regarded as a sign of puerperal infection. The specific regulation is that within 24 hours to 10 days after delivery, when the body temperature reaches or exceeds 38°C twice 12 hours apart, and the existence of other diseases (such as mastitis, urinary tract infection, upper respiratory tract infection, etc.) cannot be confirmed, it should be considered. The possibility o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/902A61P31/04A61P29/00
CPCA61K36/185A61K9/0019A61K9/0095A61K9/1652A61K9/19A61K36/11A61K36/19A61K36/27A61K36/28A61K36/29A61K36/30A61K36/31A61K36/344A61K36/486A61K36/51A61K36/59A61K36/60A61K36/704A61K36/716A61K36/718A61K36/72A61K36/73A61K36/752A61K36/88A61K36/8945A61K36/899A61K36/902A61K47/26A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 张敏
Owner 济南思拓新源医药科技有限公司
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