Traditional Chinese medicine gel for treating keratitis and preparation method and application thereof

Abstract

The invention discloses traditional Chinese medicine gel for treating keratitis and a preparation method and application thereof. The raw materials of the Chinese medicine gel for treating the keratitis include honeysuckles, flos buddlejae, divaricate saposhnikovia roots, securinega suffruticosa, mahoniae caulis, fructus viticis, herba schizonepetae, loofah sponges, common peony roots, caulis spatholobi and fatsia japonica. In preparation, a moisturizing agent, a pH regulating agent and a buffer agent are added, wherein the moisturizing agent is glycerin or propylene glycol, and the buffer agent is sodium citrate / a citric acid buffer pair, a phosphate buffer pair, a tris-hydrochloric buffer pair or a glycine-triethylamine buffer pair. The traditional Chinese medicine gel achieves the keratitis treating purpose through transdermal absorption of the medicines, rapidly eliminates symptoms including photophobia, tearing, aching pain and the like caused by the keratitis, repairs a damaged immune system, improves the body resistance, fundamentally treats the keratitis, directly acts on the eyes, is free of toxic and side effects and provides a new choice for clinical keratitis treatment and alleviation of the symptoms caused by the keratitis.

Description

technical field [0001] The invention relates to the technical field of medical application, in particular to a traditional Chinese medicine gel for treating keratitis, a preparation method and application thereof. Background technique [0002] Herpes simplex virus keratitis is the most serious common corneal disease at present, and it has a clear rising and aggravating trend in recent years. Due to recurrent attacks and increasing number of severe cases, it seriously threatens visual function, so strengthening the research on this disease has become an urgent problem to be solved in ophthalmology. The clinical manifestations of this disease are complicated. In addition to the typical shape of branches, maps and disc-shaped corneal lesions, there are also some atypical clinical changes, which bring great difficulties to diagnosis and treatment. Each type not only has unique clinical characteristics, but also has different pathogenesis and treatment principles. The various ty...

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Problems solved by technology

[0004] At present, the clinical treatment methods for herpes simplex virus keratitis mainly include: focus debridement, suitable for superficial cases, the principle is to remove infected cells and viruses through physical or chemical methods, including mechanical debridement, chemical debridement, etc. Debridement, freezing debridement, photoinactivation therapy, debridement of the lesion can only remove infected cells but not prevent virus reproduction, may damage the corneal epithelial basement membrane and stromal layer, and promote the development of lesions to the deep, cryotherapy has no effect on the vitality of HSV Antiviral drugs, such as iodinidine, cytarabine, trifluorothymidine, etc., are mostly used in the late treatment of herpes simplex virus keratitis; corticosteroids, inhibit the release of histamine and toxic lytic enzymes, and reduce inflammation Reaction and tissue damage, reduce scar formation, promote angiogenesis, but there is also the risk of damaging the immune mechanism of the body and corneal tissue; surgical treatment, suitable for deep ulcers, stromal necrotizing keratitis combined with perforation, relying on drugs and conservative treatment alone Conditions that have been ineffective, including conjunctival flap covering, anterior chamber puncture, lamellar or penetrating keratoplasty, surgical therapy has clinical surgical risks

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